BGC0001148: pheganomycin biosynthetic gene cluster from Streptomyces cirratus
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Location: 1 - 28,927 nt. (total: 28,927 nt).
This entry is originally from NCBI GenBank AB896796.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001148
Short description pheganomycin biosynthetic gene cluster from Streptomyces cirratus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • ribosomal (RiPP)
Loci
AB896796.1
via
Compounds
  • pheganomycin
Species Streptomyces cirratus [taxonomy]
References
Chemical products information
pheganomycin Evidence:
Copy SMILES
C26H42N8O9
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAP82647.1
  • pgm1
 63 - 1382 (-) peptide ligase
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    • BAP82648.1
    • pgm2
    		 1632 - 1748 (+) hypothetical protein
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      • BAP82649.1
      • pgm3
      		 1876 - 3846 (+) radical SAM domain containing protein
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        • BAP82650.1
        • pgm4
        		 3913 - 5070 (+) C-methyltransferase
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          • BAP82651.1
          • pgm5
          		 5070 - 6827 (+) ABC transporter
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            • BAP82652.1
            • pgm6
            		 6830 - 8653 (+) ABC transporter
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              • BAP82653.1
              • pgm7
              		 8663 - 9988 (-) cytochrome P450
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                • BAP82654.1
                • pgm8
                		 9985 - 11295 (-) aminotransferase
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                  • BAP82655.1
                  • pgm9
                  		 11292 - 12629 (-) enoyl-CoA hydratase like protein
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                    • BAP82656.1
                    • pgm10
                    		 12626 - 13462 (-) enoyl-CoA hydratase like protein
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                      • BAP82657.1
                      • pgm11
                      		 13486 - 14547 (-) chalcone and stilbene synthase like protein
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                        • BAP82658.1
                        • pgm12
                        		 14566 - 15849 (-) amidinotransferase
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                          • BAP82659.1
                          • pgm13
                          		 16045 - 18285 (-) hypothetical protein
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                            • BAP82660.1
                            • pgm14
                            		 18437 - 21916 (-) peptidase
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                              • BAP82661.1
                              • pgm15
                              		 22090 - 23049 (+) transcriptional regulator
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                                • BAP82662.1
                                • pgm16
                                		 23083 - 23454 (-) hypothetical protein
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                                  • BAP82663.1
                                  • pgm17
                                  		 23599 - 23955 (-) hypothetical protein
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                                    • BAP82664.1
                                    • pgm18
                                    		 24042 - 25325 (-) permease
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                                      • BAP82665.1
                                      • pgm19
                                      		 25339 - 26664 (-) non-ribosomal peptide synthetase C-domain containing protein
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                                        • BAP82666.1
                                        • pgm20
                                        		 26677 - 26922 (-) non-ribosomal peptide synthetase T-domain containing protein
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                                          • BAP82667.1
                                          • pgm21
                                          		 26919 - 28868 (-) non-ribosomal peptide synthetase A-domain containing protein
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                                            Biosynthesis information
                                            Annotation changelog

                                            Entry version: 4

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2022-10-07
                                            Update chemical activity to schema version 2.11
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 3

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2022-09-15
                                            Updated bioactivity data
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 2

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2019-10-16
                                            Migrated from v1.4
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            2019-10-16
                                            Updated reference publication(s) (MIBiG Annotathon)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            2019-10-16
                                            Updated compound(s) information (NPAtlas curation)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 1

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2015-06-12
                                            Submitted
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            Detailed domain annotation
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