BGC0001157 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001157 (Streptomyces scabiei 87.22)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	bottromycin	1	20,816	High	bottromycin A2	ribosomal:RiPP:Bottromycin

BGC0001157 - Region 1 - bottromycin

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Location: 1 - 20,816 nt. (total: 20,816 nt) Show pHMM detection rules used

Region on contig edge.

bottromycin: botH

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 20,817
Label		BGC0001157

Tailoring functions

Oxidoreductases: Cyclization Heterocyclization oxygenase

SCAB_56621: Decarboxylation, Oxidation

MITE: MITE0000044Decarboxylation, Oxidation (identity: 93.10%)
smcogs: SMCOG1007: cytochrome P450

SCAB_56661: Cyclization

MITE: MITE0000053Cyclization (identity: 89.60%)

SCAB_56671: Heterocyclization

MITE: MITE0000052Heterocyclization (identity: 80.80%)

Transferases: Methylation

SCAB_56611: Methylation

MITE: MITE0000047Methylation (identity: 90.30%)

SCAB_56651: Methylation

MITE: MITE0000046Methylation (identity: 93.40%)

SCAB_56691: Methylation

MITE: MITE0000049Methylation (identity: 92.50%)

SCAB_56701: Methylation

MITE: MITE0000045Methylation (identity: 90.60%)

Hydrolases: Hydrolysis

SCAB_56591: Hydrolysis

MITE: MITE0000048Hydrolysis (identity: 86.70%)

SCAB_56631: Hydrolysis

MITE: MITE0000050Hydrolysis (identity: 87.60%)

Lyases: oxygenase

SCAB_56621: Decarboxylation, Oxidation

MITE: MITE0000044Decarboxylation, Oxidation (identity: 93.10%)
smcogs: SMCOG1007: cytochrome P450

Isomerases: Epimerization

SCAB_56641: Epimerization

MITE: MITE0000051Epimerization (identity: 88.30%)

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001157.6	1.00	ribosomal	bottromycin A2	Streptomyces scabiei 87.22
BGC0000468.5	0.89	ribosomal	bottromycin A2	Streptomyces bottropensis DSM40262
BGC0000469.6	0.86	ribosomal	bottromycin A2	Streptomyces sp. BC16019
BGC0000470.6	0.82	ribosomal	bottromycin D	Streptomyces sp. WMMB272
BGC0002127.3	0.46	PKS	flaviolin, 1,3,6,8-tetrahydroxynaphthalene	Streptomyces coelicolor A3(2)
BGC0001485.4	0.43	other (other)	chuangxinmycin	Actinoplanes tsinanensis
BGC0001223.5	0.42	other (other)	hydroxysporine	uncultured bacterium
BGC0002347.3	0.41	other (other)	cyanogramide, cyanogramide B, cyanogramide C, cyanogramide D	Actinoalloteichus caeruleus WH1-2216-6
BGC0000902.4	0.41	PKS	flaviolin	Saccharopolyspora erythraea NRRL 2338
BGC0002000.4	0.39	PKS	setomimycin	Streptomyces aurantiacus JA 4570

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001157.6	1.00	ribosomal	bottromycin A2	Streptomyces scabiei 87.22
BGC0000468.5	0.89	ribosomal	bottromycin A2	Streptomyces bottropensis DSM40262
BGC0000469.6	0.86	ribosomal	bottromycin A2	Streptomyces sp. BC16019
BGC0000470.6	0.82	ribosomal	bottromycin D	Streptomyces sp. WMMB272
BGC0002127.3	0.46	PKS	flaviolin, 1,3,6,8-tetrahydroxynaphthalene	Streptomyces coelicolor A3(2)
BGC0001485.4	0.43	other (other)	chuangxinmycin	Actinoplanes tsinanensis
BGC0001223.5	0.42	other (other)	hydroxysporine	uncultured bacterium
BGC0002347.3	0.41	other (other)	cyanogramide, cyanogramide B, cyanogramide C, cyanogramide D	Actinoalloteichus caeruleus WH1-2216-6
BGC0000902.4	0.41	PKS	flaviolin	Saccharopolyspora erythraea NRRL 2338
BGC0002000.4	0.39	PKS	setomimycin	Streptomyces aurantiacus JA 4570

Similar known clusters from MIBiG 4.0