BGC0001199: akaeolide biosynthetic gene cluster from Streptomyces sp. NBRC 109706
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Location: 619,196 - 682,595 nt. (total: 63,400 nt).
This entry is originally from NCBI GenBank BBOM01000011.1, but has been modified (see Modifications tab for details).

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
Modifications
General information about the BGC
MIBiG accession BGC0001199
Short description akaeolide biosynthetic gene cluster from Streptomyces sp. NBRC 109706
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
BBOM01000011.1
619196 - 682595
via
Compounds
  • akaeolide
Species Streptomyces sp. NBRC 109706 [taxonomy]
References
Chemical products information
akaeolide Evidence:
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C22H32O6
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ctg1_orf512
 619196 - 620437 (+)
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    • ctg1_orf513
    		 620488 - 621216 (+)
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      • ctg1_orf514
      		 621346 - 622293 (+)
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        • ctg1_orf515
        		 622420 - 623166 (+)
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          • ctg1_orf516
          		 623200 - 624084 (+)
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            • ctg1_orf517
            		 624084 - 624575 (+)
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              • ctg1_orf518
              		 624759 - 626357 (+)
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                • ctg1_orf519
                		 626426 - 629269 (+)
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                  • ctg1_orf520
                  		 629866 - 631464 (+)
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                    • ctg1_orf521
                    		 632598 - 647351 (+)
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                      • ctg1_orf522
                      		 647407 - 658212 (+)
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                        • ctg1_orf523
                        		 658257 - 666962 (+)
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                          • ctg1_orf524
                          		 666982 - 670950 (+)
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                            • ctg1_orf525
                            		 670980 - 672176 (+)
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                              • ctg1_orf526
                              		 672250 - 672597 (+)
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                                • ctg1_orf527
                                		 672734 - 672970 (+)
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                                  • ctg1_orf528
                                  		 672990 - 674198 (+)
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                                    • ctg1_orf529
                                    		 674424 - 675113 (+)
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                                      • ctg1_orf530
                                      		 675238 - 676734 (+)
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                                        • ctg1_orf531
                                        		 676857 - 677507 (+)
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                                          • ctg1_orf532
                                          		 677639 - 677968 (+)
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                                            • ctg1_orf533
                                            		 678281 - 679654 (+)
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                                              • ctg1_orf534
                                              		 679657 - 680679 (+)
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                                                • ctg1_orf535
                                                		 680676 - 681536 (+)
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                                                  • ctg1_orf536
                                                  		 681576 - 682595 (+)
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                                                    Biosynthesis information
                                                    Annotation changelog

                                                    Entry version: 4

                                                    Date
                                                    Changes
                                                    Submitters
                                                    Reviewers
                                                    2022-10-07
                                                    Update chemical activity to schema version 2.11
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                    Entry version: 3

                                                    Date
                                                    Changes
                                                    Submitters
                                                    Reviewers
                                                    2022-09-15
                                                    Removed empty gene annotations
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    2022-09-15
                                                    Updated bioactivity data
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                    Entry version: 2

                                                    Date
                                                    Changes
                                                    Submitters
                                                    Reviewers
                                                    2019-10-16
                                                    Migrated from v1.4
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    2019-10-16
                                                    Updated compound(s) information (NPAtlas curation)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                    Entry version: 1

                                                    Date
                                                    Changes
                                                    Submitters
                                                    Reviewers
                                                    2015-08-17
                                                    Submitted
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    Detailed domain annotation
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                                                    Modifications to original record
                                                    • ctg1_orf512 was added
                                                    • ctg1_orf513 was added
                                                    • ctg1_orf514 was added
                                                    • ctg1_orf515 was added
                                                    • ctg1_orf516 was added
                                                    • ctg1_orf517 was added
                                                    • ctg1_orf518 was added
                                                    • ctg1_orf519 was added
                                                    • ctg1_orf520 was added
                                                    • ctg1_orf521 was added
                                                    • ctg1_orf522 was added
                                                    • ctg1_orf523 was added
                                                    • ctg1_orf524 was added
                                                    • ctg1_orf525 was added
                                                    • ctg1_orf526 was added
                                                    • ctg1_orf527 was added
                                                    • ctg1_orf528 was added
                                                    • ctg1_orf529 was added
                                                    • ctg1_orf530 was added
                                                    • ctg1_orf531 was added
                                                    • ctg1_orf532 was added
                                                    • ctg1_orf533 was added
                                                    • ctg1_orf534 was added
                                                    • ctg1_orf535 was added
                                                    • ctg1_orf536 was added