BGC0001212: nannocystin a biosynthetic gene cluster from Nannocystis sp. MB1016
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Location: 1 - 55,222 nt. (total: 55,222 nt).
This entry is originally from NCBI GenBank KT067736.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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General
Compounds
Genes
Polyketide
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001212
Short description nannocystin a biosynthetic gene cluster from Nannocystis sp. MB1016
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide (Macrolide)
Loci NCBI GenBank: KT067736.1
Compounds
  • nannocystin a
Species Nannocystis sp. MB1016 [taxonomy]
References
Chemical products information
nannocystin a
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C42H55Cl2N3O9
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ALD82521.1
  • ncyA
 519 - 7424 (+) polyketide synthase
  • Scaffold biosynthesis
Sequence-based prediction
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  • ALD82522.1
  • ncyB
 7421 - 19156 (+) polyketide synthase
  • Scaffold biosynthesis
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  • ALD82523.1
  • ncyC
 19163 - 24862 (+) polyketide synthase
  • Scaffold biosynthesis
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  • ALD82524.1
  • ncyD
 24859 - 30504 (+) polyketide synthase
  • Scaffold biosynthesis
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  • ALD82525.1
  • ncyE
 30501 - 35132 (+) non-ribosomal peptide synthase
  • Scaffold biosynthesis
Sequence-based prediction
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  • ALD82526.1
  • ncyF
 35165 - 45550 (+) non-ribosomal peptide synthase
  • Scaffold biosynthesis
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  • ALD82527.1
  • ncyG
 45582 - 47078 (-) ncyG
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  • ALD82528.1
  • ncyH
 47470 - 48693 (+) P450 protein
  • Tailoring (Monooxygenation)
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  • ALD82529.1
  • ncyI
 48962 - 49831 (+) kinase/phosphodiesterase
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  • ALD82530.1
  • ncyJ
 50197 - 50295 (+) ncyJ
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  • ALD82531.1
  • ncyK
 50557 - 50760 (+) ncyK
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  • ALD82532.1
  • ncyL
 50764 - 50901 (-) ncyL
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  • ALD82533.1
  • ncyM
 51082 - 52581 (-) halogenase
  • Tailoring (Halogenation)
Sequence-based prediction
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  • ALD82534.1
  • ncyN
 52643 - 54811 (-) heavy metal translocating P-type ATPase
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Polyketide-specific information
Subclass Macrolide
Starter unit Benzoyl-CoA
Cyclic? yes
Release type
  • Macrolactonization
NRP-specific information
Subclass N/A
Cyclic? yes
Release type
  • Macrolactonization
Thioesterase genes
  • ncyF (Type I)
Annotation changelog
MIBiG version Submitter Notes
1.2
  • Hidden contributor (ID: O4PIO7VEX2IICIP2RGFFKN3C, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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