BGC0001235: antalid biosynthetic gene cluster from Polyangium spumosum
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 50,952 nt. (total: 50,952 nt).
This entry is originally from NCBI GenBank KU245058.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001235
Short description antalid biosynthetic gene cluster from Polyangium spumosum
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
KU245058.1
via
Compounds
  • antalid
Species Polyangium spumosum [taxonomy]
References
Chemical products information
antalid Evidence:
Copy SMILES
C28H37N3O5S1
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ANI24095.1
 54 - 929 (-) hypothetical protein
    copy AA seq
    copy Nt seq
    • ANI24096.1
    		 1155 - 4700 (+) FAD-dependent oxidoreductase
      copy AA seq
      copy Nt seq
      • ANI24097.1
      		 4697 - 5671 (+) hypothetical protein
        copy AA seq
        copy Nt seq
        • ANI24098.1
        		 5818 - 6603 (+) serin protease inhibitor protein
          copy AA seq
          copy Nt seq
          • ANI24099.1
          • antA
          		 6741 - 26663 (+) polyketide synthase
            copy AA seq
            copy Nt seq
            • ANI24100.1
            • antB
            		 26678 - 40243 (+) nonribosomal peptide synthetase
              copy AA seq
              copy Nt seq
              • ANI24101.1
              		 40286 - 42706 (-) TonB-dependent siderophore receptor family protein
                copy AA seq
                copy Nt seq
                • ANI24102.1
                		 42911 - 43825 (+) hypothetical protein
                  copy AA seq
                  copy Nt seq
                  • ANI24103.1
                  		 44304 - 47114 (+) pyruvate phosphate dikinase
                    copy AA seq
                    copy Nt seq
                    • ANI24104.1
                    		 47211 - 48122 (+) acetyltransferase
                      copy AA seq
                      copy Nt seq
                      • ANI24105.1
                      		 49086 - 50000 (-) protein kinase domain protein
                        copy AA seq
                        copy Nt seq
                        Biosynthesis information

                        Biosynthetic modules

                        Name
                        Unk01
                        Type
                        nrps-type1
                        Genes
                        antB
                        Substrates
                        valine (evidence: Structure-based inference [1])
                        Integrated Monomers
                        Domains
                        adenylation
                        Name
                        Unk02
                        Type
                        nrps-type1
                        Genes
                        antB
                        Substrates
                        cysteine (evidence: Structure-based inference, Sequence-based prediction)
                        Integrated Monomers
                        Domains
                        adenylation
                        Name
                        Unk03
                        Type
                        nrps-type1
                        Genes
                        antB
                        Substrates
                        phenylalanine (evidence: Structure-based inference [1])
                        Integrated Monomers
                        Domains
                        adenylation
                        Annotation changelog

                        Entry version: 3

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2022-09-15
                        Added NRP substrate specificities
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                        Entry version: 2

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2019-10-16
                        Migrated from v1.4
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        2019-10-16
                        Updated compound(s) information (NPAtlas curation)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                        Entry version: 1

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2016-09-03
                        Submitted
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        Detailed domain annotation
                        Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                        A domain glossary is available here, and an explanation of the visualisation is available here.
                        Selected features only
                        Show module domains
                        Similar known gene clusters from MIBiG 4.0
                        Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                        Click on reference genes to show details of similarities to genes within the current region.
                        Click on an accession to open that entry in the MiBIG database.