BGC0001257 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001257 (Nodulisporium sp. ATCC74245)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	7,549	1,3,6,8-tetrahydroxynaphthalene	Polyketide	100%

BGC0001257 - Region 1 - T1PKS

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Location: 1 - 7,549 nt. (total: 7,549 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 7,550
Label		BGC0001257

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001257.1	0.55	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0001258.1	0.26	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0001906.1	0.25	Polyketide	naphthalene	Daldinia eschscholzii IFB-TL01
BGC0001265.1	0.24	Polyketide	melanin	Bipolaris oryzae
BGC0000107.1	0.23	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0000056.1	0.23	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0001284.1	0.22	Terpene	alternariol	Parastagonospora nodorum SN15
BGC0001254.1	0.18	Polyketide	ACT-Toxin II	Alternaria alternata
BGC0000046.1	0.18	Polyketide	depudecin	Alternaria brassicicola
BGC0001124.1	0.18	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001257.1	0.82	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0001258.1	0.60	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0001906.1	0.58	Polyketide	naphthalene	Daldinia eschscholzii IFB-TL01
BGC0001265.1	0.57	Polyketide	melanin	Bipolaris oryzae
BGC0000107.1	0.56	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0000056.1	0.56	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0001284.1	0.55	Terpene	alternariol	Parastagonospora nodorum SN15
BGC0001254.1	0.50	Polyketide	ACT-Toxin II	Alternaria alternata
BGC0000046.1	0.50	Polyketide	depudecin	Alternaria brassicicola
BGC0001124.1	0.50	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015

Similar known gene clusters

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 7549:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

pks1

PKS_AT (912..1212): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 91.7%; inactive: 62.5%; Methylmalonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 125.2
inactive: 70.5
Methoxymalonyl-CoA: 50.3
Methylmalonyl-CoA: 49.6
Ethylmalonyl-CoA: 25.0
2-Methylbutyryl-CoA: 23.3
CHC-CoA: 22.0
Propionyl-CoA: 18.6
Isobutyryl-CoA: 18.6
fatty_acid: 13.9
Benzoyl-CoA: 12.4
3-Methylbutyryl-CoA: 11.6
trans-1,2-CPDA: 10.0
Acetyl-CoA: 8.6