BGC0001276 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001276 (Aspergillus terreus)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	7,588	(-)-Mellein	Polyketide	100%

BGC0001276 - Region 1 - T1PKS

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Location: 1 - 7,588 nt. (total: 7,588 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 7,589
Label		BGC0001276

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001276.1	1.00	Polyketide	6-methylsalicyclic acid	Aspergillus terreus
BGC0001275.1	0.40	Polyketide	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001244.1	0.39	Polyketide	(-)-Mellein	Parastagonospora nodorum
BGC0001273.1	0.39	Polyketide	asperlactone	Aspergillus ochraceus
BGC0000160.1	0.38	Polyketide	terreic acid	Aspergillus terreus NIH2624
BGC0000056.1	0.23	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0000120.1	0.23	Polyketide	patulin	Penicillium expansum
BGC0000170.1	0.21	Polyketide	yanuthone D	Aspergillus niger ATCC 1015
BGC0001400.1	0.20	Polyketide	citreoviridin	Aspergillus terreus NIH2624
BGC0001909.1	0.20	Polyketide	strobilurin	Strobilurus tenacellus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001276.1	1.00	Polyketide	6-methylsalicyclic acid	Aspergillus terreus
BGC0001275.1	0.72	Polyketide	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001244.1	0.71	Polyketide	(-)-Mellein	Parastagonospora nodorum
BGC0001273.1	0.71	Polyketide	asperlactone	Aspergillus ochraceus
BGC0000160.1	0.71	Polyketide	terreic acid	Aspergillus terreus NIH2624
BGC0000056.1	0.56	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0000120.1	0.56	Polyketide	patulin	Penicillium expansum
BGC0000170.1	0.54	Polyketide	yanuthone D	Aspergillus niger ATCC 1015
BGC0001400.1	0.52	Polyketide	citreoviridin	Aspergillus terreus NIH2624
BGC0001909.1	0.52	Polyketide	strobilurin	Strobilurus tenacellus

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 7588:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

atX

PKS_AT (582..873): pk

ATSignature: Malonyl-CoA, Acetyl-CoA

Top 3 matches:: Malonyl-CoA: 66.7%; Acetyl-CoA: 66.7%; CE-Malonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 110.5
Ethylmalonyl-CoA: 86.5
Methoxymalonyl-CoA: 85.5
Malonyl-CoA: 76.1
Isobutyryl-CoA: 75.9
Acetyl-CoA: 70.9
2-Methylbutyryl-CoA: 59.8
Propionyl-CoA: 53.6
trans-1,2-CPDA: 42.0
Benzoyl-CoA: 37.9
3-Methylbutyryl-CoA: 33.4
fatty_acid: 31.6
CHC-CoA: 28.6
inactive: 12.9