Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001293.1:
Cluster 1Polyketide149740

BGC0001293, cyclizidine biosynthetic gene cluster from Streptomyces sp. NCIB. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: cyclizidine
PubChem ID: 101788223
SMILES string: Copy to clipboard
Molecular formula: C17H25NO3
Average molecular mass: 291.391 Da

Class-specific details

Biosynthetic class(es):
Polyketide
Polyketide synthase subclass:
Type I

Gene cluster description

Download cluster GenBank file
cyclizidine (BGC0001293). Gene Cluster 1. Biosynthetic class = Polyketide. GenBank KT327068. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. Huang W et al. (2015) Identification of the Polyketide Biosynthetic Machinery for the Indolizidine Alkaloid Cyclizidine. Org Lett 17(21):5344-7. doi: 10.1021/acs.orglett.5b02707. Epub 2015