BGC0001293: cyclizidine biosynthetic gene cluster from Streptomyces sp. NCIB 11649
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Location: 1 - 49,740 nt. (total: 49,740 nt).
This entry is originally from NCBI GenBank KT327068.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001293
Short description cyclizidine biosynthetic gene cluster from Streptomyces sp. NCIB 11649
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
KT327068.1
via
Compounds
  • cyclizidine
Species Streptomyces sp. NCIB 11649 [taxonomy]
References
Chemical products information
cyclizidine Evidence:
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C17H25N1O3
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ALP32041.1
  • cycA
 1 - 957 (+) CycA
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    • ALP32042.1
    • cycB
    		 1096 - 7512 (-) CycB
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      • ALP32043.1
      • cycC
      		 7557 - 18698 (-) CycC
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        • ALP32044.1
        • cycD
        		 18699 - 19370 (-) CycD
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          • ALP32045.1
          • cycE
          		 19375 - 30150 (-) CycE
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            • ALP32046.1
            • cycF
            		 30298 - 38082 (-) CycF
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              • ALP32047.1
              • cycG
              		 38157 - 38984 (-) CycG
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                • ALP32048.1
                • cycH
                		 39038 - 40366 (-) CycH
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                  • ALP32049.1
                  • cycI
                  		 40420 - 42021 (-) CycI
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                    • ALP32050.1
                    • cycJ
                    		 42270 - 42665 (+) CycJ
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                      • ALP32051.1
                      • cycK
                      		 42803 - 43990 (-) CycK
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                        • ALP32052.1
                        • cycL
                        		 44213 - 44737 (+) CycL
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                          • ALP32053.1
                          • cycM
                          		 44861 - 45328 (-) CycM
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                            • ALP32054.1
                            • cycN
                            		 45332 - 46294 (-) CycN
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                              • ALP32055.1
                              • cycO
                              		 46517 - 47308 (-) CycO
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                                • ALP32056.1
                                • cycP
                                		 47614 - 48258 (+) CycP
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                                  • ALP32057.1
                                  • cycQ
                                  		 48478 - 49740 (-) CycQ
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                                    Biosynthesis information
                                    Annotation changelog

                                    Entry version: 4

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2022-10-07
                                    Update chemical activity to schema version 2.11
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                    Entry version: 3

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2022-09-15
                                    Updated bioactivity data
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                    Entry version: 2

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2019-10-16
                                    Migrated from v1.4
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    2019-10-16
                                    Updated compound(s) information (NPAtlas curation)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                    Entry version: 1

                                    Date
                                    Changes
                                    Submitters
                                    Reviewers
                                    2015-12-24
                                    Submitted
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                    Detailed domain annotation
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