BGC0001298: 4-Z-annimycin biosynthetic gene cluster from Streptomyces calvus
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Location: 1 - 41,001 nt. (total: 41,001 nt).
This entry is originally from NCBI GenBank KF683117.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
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Biosynthesis
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001298
Short description 4-Z-annimycin biosynthetic gene cluster from Streptomyces calvus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Type I)
Loci
KF683117.1
via
Compounds
  • 4-Z-annimycin
  • 4-E-annimycin
Species Streptomyces calvus [taxonomy]
References
Chemical products information
4-Z-annimycin Evidence: NMR [1], Mass spectrometry [1]
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C19H25N1O4
Chemical database entries
PubCHEM
NPAtlas
ChEBI
4-E-annimycin Evidence: NMR [1], Mass spectrometry [1]
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C19H25N1O4
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AGY30672.1
 30 - 572 (+) phosphohistidine phosphatase
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    • AGY30673.1
    		 627 - 1253 (+) YigZ family protein
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      • AGY30674.1
      		 1751 - 3319 (+) amide synthetase
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        • AGY30678.1
        		 3375 - 4664 (+) 5-aminolevulinate synthase
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          • AGY30675.1
          		 4661 - 6202 (+) acyl-CoA ligase
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            • AGY30676.1
            		 6462 - 25052 (+) type I polyketide synthase
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              • AGY30677.1
              		 25064 - 36568 (+) type I polyketide synthase
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                • AGY30679.1
                		 37033 - 38610 (+) membrane efflux transporter
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                  • AGY30680.1
                  		 38892 - 40919 (+) ATP-dependent helicase
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                    Biosynthesis information

                    Biosynthetic paths

                    2-amino-3-hydroxycyclopentenone
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                    Pathway: ann3 > ann2 [2]
                    Subcluster
                    Precursor
                    Annotation changelog

                    Entry version: next

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2024-07-28
                    MIBiG v4 annotathon
                    • (ID: SDAWYQYFQDDVDNDD7ZO2XI6Z)
                    • (ID: AA7SE7MC65QS2IJNSQXWZD7I)
                    • (ID: SJG3CBEHSM6A3I74YXLH6GLA)
                    • (ID: MGLE5JJ3S32DQA3YR5WPYH4W)
                    • (ID: 2U5WMR7MBJ4KI76XQF5437F7)
                    • (ID: 4CEPXXFDQQ46VQJXBT4B4AUO)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 3

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2022-09-15
                    Updated bioactivity data
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    2022-09-15
                    Added AMP-binding domain substrate specificities
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 2

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2019-10-16
                    Migrated from v1.4
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 1

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2015-12-24
                    Submitted
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    Detailed domain annotation
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