BGC0001303: lobosamide A biosynthetic gene cluster from Micromonospora sp. RL09-050-HVF-A
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Location: 1 - 108,672 nt. (total: 108,672 nt).
This entry is originally from NCBI GenBank KT209587.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001303
Short description lobosamide A biosynthetic gene cluster from Micromonospora sp. RL09-050-HVF-A
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: KT209587.1
Compounds
  • lobosamide A
  • lobosamide B
  • lobosamide C
Species Micromonospora sp. RL09-050-HVF-A [taxonomy]
References
Chemical products information
lobosamide A
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C29H41N1O5
Chemical database entries
NPAtlas
lobosamide B
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C29H41N1O5
Chemical database entries
NPAtlas
lobosamide C
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C29H41N1O4
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ALA09339.1
  • ORF1
 419 - 1432 (-) hypothetical protein
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  • ALA09340.1
  • ORF2
 1515 - 2462 (-) hypothetical protein
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  • ALA09341.1
  • ORF3
 2643 - 3470 (+) hypothetical protein
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  • ALA09342.1
  • ORF4
 3452 - 3823 (+) hypothetical protein
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  • ALA09343.1
  • ORF5
 3854 - 4882 (+) hypothetical protein
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  • ALA09344.1
  • ORF6
 4906 - 5670 (+) hypothetical protein
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  • ALA09345.1
  • ORF7
 5843 - 7495 (+) hypothetical protein
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  • ALA09346.1
  • ORF8
 8034 - 13499 (-) hypothetical protein
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  • ALA09347.1
  • ORF9
 13704 - 14393 (-) hypothetical protein
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  • ALA09348.1
  • ORF10
 14510 - 14782 (+) hypothetical protein
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  • ALA09349.1
  • ORF11
 14779 - 15792 (+) hypothetical protein
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  • ALA09350.1
  • ORF12
 15911 - 16498 (+) hypothetical protein
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  • ALA09351.1
  • ORF13
 16699 - 17787 (+) hypothetical protein
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  • ALA09352.1
  • ORF14
 17864 - 18082 (+) hypothetical protein
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  • ALA09353.1
  • ORF15
 18407 - 19654 (+) hypothetical protein
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  • ALA09354.1
  • lobA
 20001 - 25313 (+) type I modular PKS
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  • ALA09355.1
  • lobB
 25497 - 34541 (+) type I modular PKS
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  • ALA09356.1
  • lobC
 34582 - 39342 (+) type I modular PKS
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  • ALA09357.1
  • lobD
 39402 - 48341 (+) type I modular PKS
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  • ALA09358.1
  • lobE
 48338 - 52861 (+) type I modular PKS
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  • ALA09359.1
  • lobF
 53029 - 55590 (+) type I modular PKS
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  • ALA09360.1
  • lobG
 55614 - 56519 (+) peptidase
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  • ALA09361.1
  • lobH
 56632 - 57075 (-) transcriptional regulator
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  • ALA09362.1
  • lobI
 57151 - 57294 (+) aldo/keto reductase family oxidoreductase
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  • ALA09363.1
  • lobJ
 57294 - 58061 (+) aldo/keto reductase family oxidoreductase
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  • ALA09364.1
  • lobK
 58127 - 58381 (-) ACP starter unit biosynthesis protein
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  • ALA09365.1
  • lobL
 58576 - 60135 (+) AMP-dependent synthetase and ligase
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  • ALA09366.1
  • lobM
 60277 - 61821 (-) AMP-dependent synthetase and ligase
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  • ALA09367.1
  • lobN
 61847 - 62776 (-) amalonyl CoA-acyl carrier protein transacylase
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  • ALA09368.1
  • lobO
 62845 - 64101 (-) aminotransferase
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  • ALA09369.1
  • lobP
 64130 - 65476 (-) glutamate 2,3- aminomutase
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  • ALA09370.1
  • lobQ
 65834 - 67021 (+) cytochrome P450
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  • ALA09371.1
  • lobR
 67391 - 88672 (+) type I modular PKS
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  • ALA09372.1
  • lobS
 89289 - 89897 (-) transcriptional regulator
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  • ALA09373.1
  • lobT
 89979 - 91712 (+) drug resistance transporter EmrB/QacA
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  • ALA09374.1
  • lobU
 92169 - 92804 (+) thioesterase
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  • ALA09375.1
  • lobV
 94084 - 96030 (+) transcriptional regulator
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  • ALA09376.1
  • lobW
 96015 - 96917 (+) transcriptional regulator
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  • ALA09377.1
  • lobX
 97058 - 97864 (+) ABC transporter
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  • ALA09378.1
  • lobY
 97864 - 100428 (+) ABC transporter
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  • ALA09379.1
  • lobZ
 100629 - 101246 (-) LuxR family DNA-binding response regulator
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  • ALA09380.1
  • lob1
 101255 - 102580 (-) sensor histidine kinase
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  • ALA09381.1
  • lob2
 102577 - 104091 (-) serine/threonine protein kinase
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  • ALA09382.1
  • ORF16
 104444 - 106345 (+) hypothetical protein
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  • ALA09383.1
  • ORF17
 106356 - 107378 (+) hypothetical protein
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  • ALA09384.1
  • ORF18
 107488 - 108348 (+) hypothetical protein
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Annotation changelog
MIBiG version Submitter Notes
1.2
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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