Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001303.1:
Cluster 1Polyketide1108672

BGC0001303, lobosamide biosynthetic gene cluster from Micromonospora sp. RL09-050-HVF-A. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: lobosamide

Class-specific details

Biosynthetic class(es):
Polyketide
Polyketide synthase subclass:
Type I

Gene cluster description

lobosamide (BGC0001303). Gene Cluster 1. Biosynthetic class = Polyketide. GenBank KT209587. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. Schulze CJ et al. (2015) Genome-Directed Lead Discovery: Biosynthesis, Structure Elucidation, and Biological Evaluation of Two Families of Polyene Macrolactams against Trypanosoma brucei. ACS Chem Biol 10(10):2373-81. doi: 10.1021/acschembio.5b00308. Epub