BGC0001338: citrinin biosynthetic gene cluster from Monascus ruber
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Location: 1 - 42,813 nt. (total: 42,813 nt).
This entry is originally from NCBI GenBank KT781075.1.

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core biosynthetic genes
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Gene details
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General
Compounds
Genes
Polyketide
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001338
Short description citrinin biosynthetic gene cluster from Monascus ruber
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide (Other)
Loci NCBI GenBank: KT781075.1
Compounds
  • citrinin
Species Monascus ruber [taxonomy]
References
Chemical products information
citrinin
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C13H14O5
Chemical database entries
NPAtlas
ChemSpider
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ALI92648.1
  • citC
 274 - 2190 (-) CitC oxidoreductase
  • Tailoring (Oxidation)
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  • ALI92649.1
  • citE
 2400 - 3342 (-) CitE dehydrogenase
  • Tailoring (Reduction)
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  • ALI92650.1
  • mrl5
 3863 - 4371 (+) MRL5 glyoxalase-like domain
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  • ALI92651.1
  • citD
 4816 - 6321 (+) CitD dehydrogenase
  • Tailoring (Oxidation)
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  • ALI92652.1
  • mrl3
 6674 - 8390 (+) MRL3 Zn(II)2Cys6 Transcriptional regulator
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  • ALI92653.1
  • citB
 8845 - 9834 (-) CitB Fe(II)-dependent oxygenase
  • Tailoring (Hydroxylation)
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  • ALI92654.1
  • citA
 10334 - 11119 (+) CitA serine hydrolase
  • Unknown
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  • ALI92655.1
  • citS
 12814 - 20651 (+) CitS citrinin polyketide synthase
  • Scaffold biosynthesis
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  • ALI92656.1
  • mrr1
 20912 - 22589 (-) MRR1 Major Facilitator Superfamily (MFS) protein
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  • ALI92657.1
  • mrr2
 25050 - 26171 (+) MRR2 histidine phosphatase
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  • ALI92658.1
  • mrr3
 27029 - 28619 (+) MRR3 unknown protein
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  • ALI92659.1
  • mrr4
 29783 - 32025 (+) MRR4 WD40 protein
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  • ALI92660.1
  • mrr5
 34868 - 35533 (-) MRR5 carbonic anhydrases
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  • ALI92661.1
  • mrr6
 37004 - 37706 (-) MRR6 unknown protein
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  • ALI92662.1
  • mrr7
 38452 - 39771 (+) MRR7 enoyl-(Acyl carrier protein) reductase
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  • ALI92663.1
  • mrr8
 40650 - 42813 (+) MRR8 AMP-binding enzyme
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Polyketide-specific information
Subclass Other
Starter unit Acetyl-CoA
Cyclic? yes
Release type
  • Reductive release
Polyketide-synthases
Genes Properties Modules
citS Synthase subclass: Iterative type I
Iterative PKS type: Non-reducing, C2-C7 first
Iteration counts: 4
Annotation changelog
MIBiG version Submitter Notes
1.3
  • Hidden contributor (ID: 3XTF2R3BHL5LPPSMGJ2QHJQC, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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