BGC0001343 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001343 (Stigmatella aurantiaca Sg a15)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	HR-T2PKS	1	19,349	High	aurachin A/aurachin D	PKS

BGC0001343 - Region 1 - HR-T2PKS

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Location: 1 - 19,349 nt. (total: 19,349 nt) Show pHMM detection rules used

Region on contig edge.

HR-T2PKS: (hr-t2pks-ksa and (t2fas or APE_KS2 or ketoacyl-synt))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

NRPS/PKS domains

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 19,350
Label		BGC0001343

Tailoring functions

Hydrolases: dehalogenase

orf11: haloalkane dehalogenase

smcogs: SMCOG1262: haloalkane dehalogenase

Ligases: ligase synthase

auaC: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

auaD: Beta-ketoacyl synthase

smcogs: SMCOG1093: Beta-ketoacyl synthase

auaE: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

auaEII: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001343.3	0.97	PKS	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0001240.4	0.59	NRPS	serinocyclin A, serinocyclin B	Metarhizium robertsii
BGC0002000.4	0.47	PKS	setomimycin	Streptomyces aurantiacus JA 4570
BGC0002591.2	0.47	PKS, terpene	aurachin C, aurachin D, aurachin SS	Streptomyces sp.
BGC0000272.3	0.44	PKS	spore pigment	Streptomyces collinus
BGC0000231.5	0.44	PKS	griseusin A, griseusin B	Streptomyces griseus
BGC0002711.2	0.43	PKS	nostovalerolactone, 9-dehydronostovalerolactone	Nostoc punctiforme PCC 73102
BGC0000234.5	0.43	PKS	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001895.4	0.42	PKS	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001
BGC0001197.5	0.42	PKS	frankiamicin	Frankia sp. EAN1pec

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001343.3	0.97	PKS	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0001240.4	0.59	NRPS	serinocyclin A, serinocyclin B	Metarhizium robertsii
BGC0002000.4	0.47	PKS	setomimycin	Streptomyces aurantiacus JA 4570
BGC0002591.2	0.47	PKS, terpene	aurachin C, aurachin D, aurachin SS	Streptomyces sp.
BGC0000272.3	0.44	PKS	spore pigment	Streptomyces collinus
BGC0000231.5	0.44	PKS	griseusin A, griseusin B	Streptomyces griseus
BGC0002711.2	0.43	PKS	nostovalerolactone, 9-dehydronostovalerolactone	Nostoc punctiforme PCC 73102
BGC0000234.5	0.43	PKS	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001895.4	0.42	PKS	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001
BGC0001197.5	0.42	PKS	frankiamicin	Frankia sp. EAN1pec

Similar known clusters from MIBiG 4.0

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS substrates

NRPS/PKS substrate predictions

auaEII: X

AMP-binding (22..420): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: TFGNVAGHIK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

auaE: X

AMP-binding (18..415): X

nrpys: Gly, Ala, Val, Leu, Ile, Abu, Ival

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: GGNFVAGHIK
Nearest Stachelhaus code(s):: diOH-Bz AANFVSGAIK (44% 8Å match)
Stachelhaus code match:: 60% (weak)

Link to PARAS substrate predictor