BGC0001371: echinocandin B biosynthetic gene cluster from Aspergillus nidulans NRRL 8112
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Location: 1 - 56,631 nt. (total: 56,631 nt).
This entry is originally from NCBI GenBank KT806042.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
NRP
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001371
Short description echinocandin B biosynthetic gene cluster from Aspergillus nidulans NRRL 8112
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: KT806042.1
Compounds
  • echinocandin B
Species Aspergillus nidulans NRRL 8112 [taxonomy]
References
Chemical products information
echinocandin B
Copy SMILES
C52H81N7O16
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AMM63164.1
  • aniB
 973 - 3987 (-) AniB
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  • AMM63170.1
  • aniC
 4158 - 5596 (-) AniC
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  • AMM63171.1
  • aniD
 5801 - 7152 (+) AniD
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  • AMM63167.1
  • aniE
 7377 - 9253 (+) AniE
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  • AMM63174.1
  • aniF
 9379 - 10480 (-) AniF
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  • AMM63168.1
  • aniF2
 11854 - 13521 (-) AniF2
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  • AMM63162.1
  • aniA
 14131 - 36072 (+) AniA
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  • AMM63172.1
  • aniG
 36316 - 37468 (+) AniG
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  • AMM63169.1
  • aniH
 37834 - 39399 (+) AniH
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  • AMM63166.1
  • aniI
 39468 - 41408 (-) AniI
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  • AMM63165.1
  • aniJ
 42952 - 45002 (+) AniJ
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  • AMM63173.1
  • aniK
 45200 - 46315 (-) AniK
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  • AMM63163.1
  • aniL
 46571 - 51788 (+) AniL
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
aniA
Module ?
Specificity: ornithine
Evidence for specificity:
  • Radio labelling
  • Structure-based inference
Module ?
Specificity: threonine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: proline
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: homotyrosine
Evidence for specificity:
  • Radio labelling
  • Structure-based inference
Module ?
Specificity: threonine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: 3S-hydroxy-4S-methylproline
Evidence for specificity:
  • Structure-based inference
aniI
Module ?
Specificity: linoleic acid
Evidence for specificity:
  • Structure-based inference
Annotation changelog
MIBiG version Submitter Notes
1.3
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added NRP substrate specificities
Detailed domain annotation
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