BGC0001393: lugdunin biosynthetic gene cluster from Staphylococcus lugdunensis N920143
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 850,457 - 881,240 nt. (total: 30,784 nt).
This entry is originally from NCBI GenBank FR870271.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001393
Short description lugdunin biosynthetic gene cluster from Staphylococcus lugdunensis N920143
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: FR870271.1
Compounds
  • lugdunin
Species Staphylococcus lugdunensis N920143 [taxonomy]
References
Chemical products information
lugdunin
Copy SMILES
C40H62N8O6S1
Chemical database entries
PubCHEM
ChemSpider
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • SLUG_08030
  • CCB53257.1
850460 - 850969 (-) conserved hypothetical protein
copy AA seq
copy Nt seq
  • SLUG_08040
  • CCB53258.1
851060 - 851299 (+) conserved hypothetical protein
copy AA seq
copy Nt seq
  • SLUG_08050
  • CCB53259.1
851286 - 852176 (+) ABC transporter family protein
copy AA seq
copy Nt seq
  • SLUG_08060
  • CCB53260.1
852173 - 852937 (+) conserved hypothetical membrane protein
copy AA seq
copy Nt seq
  • SLUG_08070
  • CCB53261.1
852950 - 853663 (+) ABC transporter family protein
copy AA seq
copy Nt seq
  • SLUG_08080
  • CCB53262.1
853656 - 855197 (+) hypothetical membrane protein
copy AA seq
copy Nt seq
  • SLUG_08090
  • CCB53263.1
855424 - 856014 (+) TetR family transcriptional regulator
copy AA seq
copy Nt seq
  • SLUG_08100
  • CCB53264.1
856040 - 863164 (+) non-ribosomal peptide synthetase
copy AA seq
copy Nt seq
  • SLUG_08110
  • CCB53265.1
863154 - 863528 (+) hypothetical protein
copy AA seq
copy Nt seq
  • SLUG_08120
  • CCB53266.1
863681 - 867373 (+) non-ribosomal peptide synthetase
copy AA seq
copy Nt seq
  • SLUG_08130
  • CCB53267.1
867391 - 876204 (+) non-ribosomal peptide synthetase
copy AA seq
copy Nt seq
  • SLUG_08140
  • CCB53268.1
876201 - 876887 (+) Thioesterase family protein
copy AA seq
copy Nt seq
  • SLUG_08150
  • CCB53269.1
876925 - 878664 (+) AMP-binding enzyme
copy AA seq
copy Nt seq
  • SLUG_08160
  • CCB53270.1
878672 - 879325 (+) hypotheical protein
copy AA seq
copy Nt seq
  • SLUG_08170
  • CCB53271.1
880578 - 881237 (+) monooxygenase family protein
copy AA seq
copy Nt seq
NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
SLUG_08100
Module ?
Specificity: valine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: tryptophan
Evidence for specificity:
  • Structure-based inference
SLUG_08120
Module ?
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
SLUG_08130
Module ?
Specificity: valine
Evidence for specificity:
  • Structure-based inference
SLUG_08150
Module ?
Specificity: cysteine
Evidence for specificity:
  • Structure-based inference
Annotation changelog
MIBiG version Submitter Notes
1.3
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.