BGC0001394: phenalamide A2 biosynthetic gene cluster from Myxococcus stipitatus DSM 14675
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Location: 5,512,653 - 5,568,893 nt. (total: 56,241 nt).
This entry is originally from NCBI GenBank CP004025.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001394
Short description phenalamide A2 biosynthetic gene cluster from Myxococcus stipitatus DSM 14675
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
CP004025.1
5512653 - 5568893
via
Compounds
  • phenalamide A2
Species Myxococcus stipitatus DSM 14675 [taxonomy]
References
Chemical products information
phenalamide A2 Evidence:
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C32H45N1O3
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • MYSTI_04318
  • AGC45616.1
 5512656 - 5513477 (-) iron-chelator utilization protein
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    • MYSTI_04319
    • AGC45617.1
    		 5513696 - 5515117 (-) hypothetical protein
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      • MYSTI_04320
      • AGC45618.1
      		 5515262 - 5519788 (-) non-ribosomal peptide synthetase
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        • MYSTI_04321
        • AGC45619.1
        		 5519785 - 5526216 (-) polyketide synthase
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          • MYSTI_04322
          • AGC45620.1
          		 5526213 - 5541800 (-) polyketide synthase
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            • MYSTI_04323
            • AGC45621.1
            		 5541803 - 5547361 (-) polyketide synthase
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              • MYSTI_04324
              • AGC45622.1
              		 5547378 - 5552951 (-) polyketide synthase
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                • MYSTI_04325
                • AGC45623.1
                		 5552948 - 5558590 (-) polyketide synthase
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                  • MYSTI_04326
                  • AGC45624.1
                  		 5558613 - 5565143 (-) polyketide synthase
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                    • MYSTI_04327
                    • AGC45625.1
                    		 5565140 - 5566882 (-) alpha keto acid dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase
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                      • MYSTI_04328
                      • AGC45626.1
                      		 5566882 - 5567859 (-) pyruvate dehydrogenase subunit beta
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                        • MYSTI_04329
                        • AGC45627.1
                        		 5567856 - 5568890 (-) pyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase subunit alpha
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                          Biosynthesis information

                          Biosynthetic modules

                          Name
                          Unk01
                          Type
                          nrps-type1
                          Genes
                          MYSTI_04320
                          Substrates
                          alanine (evidence: Structure-based inference [1])
                          Integrated Monomers
                          Domains
                          adenylation
                          Annotation changelog

                          Entry version: 4

                          Date
                          Changes
                          Submitters
                          Reviewers
                          2022-10-07
                          Update chemical activity to schema version 2.11
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                          Entry version: 3

                          Date
                          Changes
                          Submitters
                          Reviewers
                          2022-09-15
                          Updated bioactivity data
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          2022-09-15
                          Added NRP substrate specificities
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                          Entry version: 2

                          Date
                          Changes
                          Submitters
                          Reviewers
                          2019-10-16
                          Migrated from v1.4
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          2019-10-16
                          Updated compound(s) information (NPAtlas curation)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                          Entry version: 1

                          Date
                          Changes
                          Submitters
                          Reviewers
                          2016-09-03
                          Submitted
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          Detailed domain annotation
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