BGC0001400 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001400 (Aspergillus terreus NIH2624)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	T1PKS	1	47,525	High	citreoviridin	PKS

BGC0001400 - Region 1 - T1PKS

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Location: 1 - 47,525 nt. (total: 47,525 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

NRPS/PKS domains

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 47,526
Label		BGC0001400

Tailoring functions

Ligases: synthase

ATEG_09617: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001400.3	1.00	PKS	citreoviridin	Aspergillus terreus NIH2624
BGC0002192.3	0.75	PKS	FR901512	fungal sp. No.14919
BGC0001254.3	0.75	PKS	ACT-Toxin II	Alternaria alternata
BGC0001268.4	0.68	NRPS, PKS	fusarin C	Fusarium fujikuroi
BGC0001244.3	0.66	PKS	(-)-Mellein	Parastagonospora nodorum
BGC0001275.3	0.66	PKS	6-methylsalicyclic acid	Glarea lozoyensis
BGC0002191.2	0.65	PKS	prolipyrone B, gibepyrone D	Fusarium graminearum PH-1
BGC0001258.3	0.63	PKS	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0002154.2	0.62	PKS	1,3,5,8-tetrahydroxynapthalene, 1-(alpha-l-(2-O-methyl)-6-deoxymannopyranosyloxy)-3,6,8-trimethoxynaphthalene	Pyricularia oryzae 70-15
BGC0000107.3	0.62	PKS	naphthopyrone	Aspergillus nidulans FGSC A4

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001400.3	1.00	PKS	citreoviridin	Aspergillus terreus NIH2624
BGC0002192.3	0.75	PKS	FR901512	fungal sp. No.14919
BGC0001254.3	0.75	PKS	ACT-Toxin II	Alternaria alternata
BGC0001268.4	0.68	NRPS, PKS	fusarin C	Fusarium fujikuroi
BGC0001244.3	0.66	PKS	(-)-Mellein	Parastagonospora nodorum
BGC0001275.3	0.66	PKS	6-methylsalicyclic acid	Glarea lozoyensis
BGC0002191.2	0.65	PKS	prolipyrone B, gibepyrone D	Fusarium graminearum PH-1
BGC0001258.3	0.63	PKS	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0002154.2	0.62	PKS	1,3,5,8-tetrahydroxynapthalene, 1-(alpha-l-(2-O-methyl)-6-deoxymannopyranosyloxy)-3,6,8-trimethoxynaphthalene	Pyricularia oryzae 70-15
BGC0000107.3	0.62	PKS	naphthopyrone	Aspergillus nidulans FGSC A4

Similar known clusters from MIBiG 4.0

Module view

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Detailed domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 47525:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Me-pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ATEG_09617: pk

PKS_AT (474..789): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 58.3%; Ethylmalonyl-CoA: 54.2%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 77.5
Methoxymalonyl-CoA: 63.9
Ethylmalonyl-CoA: 57.7
Malonyl-CoA: 55.7
Isobutyryl-CoA: 49.9
Propionyl-CoA: 29.8
trans-1,2-CPDA: 28.2
Benzoyl-CoA: 26.9
fatty_acid: 16.7
2-Methylbutyryl-CoA: 15.8
CHC-CoA: 5.2
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

Link to PARAS substrate predictor