Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001409.1:
Cluster 1Polyketide159215

BGC0001409, dutomycin biosynthetic gene cluster from Streptomyces minoensis. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: dutomycin
SMILES string: Copy to clipboard
Molecular formula: C44H54O17
Average molecular mass: 854.899 Da

Class-specific details

Biosynthetic class(es):
Polyketide
Polyketide synthase subclass:
Type II

Gene cluster description

dutomycin (BGC0001409). Gene Cluster 1. Biosynthetic class = Polyketide. GenBank KP710956. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. Sun L et al. (2016) Characterization of Three Tailoring Enzymes in Dutomycin Biosynthesis and Generation of a Potent Antibacterial Analogue. ACS Chem Biol 11(7):1992-2001. doi: 10.1021/acschembio.6b00245. Epub