BGC0001415: althiomycin biosynthetic gene cluster from Serratia marcescens subsp. marcescens Db11
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Location: 2,414,944 - 2,445,231 nt. (total: 30,288 nt).
This entry is originally from NCBI GenBank HG326223.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001415
Short description althiomycin biosynthetic gene cluster from Serratia marcescens subsp. marcescens Db11
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide
Loci NCBI GenBank: HG326223.1
Compounds
  • althiomycin
Species Serratia marcescens subsp. marcescens Db11 [taxonomy]
References
Chemical products information
althiomycin [synonyms: Matamycin, Altiomycin]
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C16H17N5O6S2
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • SMDB11_2288
  • CDG12863.1
 2414947 - 2415681 (-) putative thioesterase
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  • SMDB11_2289
  • CDG12864.1
 2415828 - 2431871 (-) non-ribosomal peptide synthetase
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  • SMDB11_2290
  • CDG12865.1
 2431874 - 2439004 (-) non-ribosomal peptide synthetase
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  • SMDB11_2291
  • CDG12866.1
 2439026 - 2439949 (-) hypothetical protein
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  • SMDB11_2292
  • CDG12867.1
 2439952 - 2440908 (-) hypothetical protein
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  • SMDB11_2293
  • CDG12868.1
 2441007 - 2442209 (-) putative drug efflux protein
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  • SMDB11_2294
  • CDG12869.1
  • bss
 2442494 - 2443843 (-) bacteriocin 28b
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  • SMDB11_2295
  • CDG12870.1
 2444149 - 2445228 (+) hypothetical protein
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
SMDB11_2289
Module ?
Specificity: glycine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: cysteine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: serine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
SMDB11_2290
Module ?
Specificity: cysteine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: glycine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Annotation changelog
MIBiG version Submitter Notes
1.3
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (MIBiG Annotathon)
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Hidden contributor (ID: CUSGWVK3I4TVHJH7NHPFAP2L, no GDPR consent given).
  • Cleaned up synonym list
  • Added missing polyketide class
  • Added NRP substrate specificities
Detailed domain annotation
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