BGC0001440 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001440 (Kitasatospora cystarginea)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	betalactone	1	13,771	High	cystargolide A/cystargolide B	other:other

BGC0001440 - Region 1 - betalactone

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Location: 1 - 13,771 nt. (total: 13,771 nt) Show pHMM detection rules used

Region on contig edge.

betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 13,772
Label		BGC0001440

Tailoring functions

Transferases: methyltransferase

cysG: methyltransferase

smcogs: SMCOG1089: methyltransferase

Hydrolases: hydrolase

ARO49558.1: alpha/beta hydrolase fold protein

smcogs: SMCOG1036: alpha/beta hydrolase fold protein

cysE: alpha/beta hydrolase fold protein

smcogs: SMCOG1036: alpha/beta hydrolase fold protein

Ligases: ligase synthase

ARO49567.1: 3-oxoacyl-(acyl carrier protein) synthase III

smcogs: SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III

cysA: 2-isopropylmalate synthase

smcogs: SMCOG1271: 2-isopropylmalate synthase

cysF: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001440.5	1.00	other (other)	cystargolide A, cystargolide B	Kitasatospora cystarginea
BGC0001441.5	0.48	other (other)	belactosin A, belactosin C	Streptomyces sp.
BGC0002554.2	0.43	other (other)	carquinostatin A, carquinostatin B	Streptomyces exfoliatus
BGC0001948.3	0.43	other (other)	naseseazine C, C3-aryl pyrroloindolines	Streptomyces sp.
BGC0002711.2	0.42	PKS	nostovalerolactone, 9-dehydronostovalerolactone	Nostoc punctiforme PCC 73102
BGC0001895.4	0.42	PKS	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001
BGC0001080.5	0.41	other (phenazine)	endophenazine A, endophenazine B	Streptomyces anulatus
BGC0000131.5	0.41	PKS	pyrrolomycin	Streptomyces sp. UC 11065
BGC0001903.3	0.41	other (other)	neocarazostatin A	Streptomyces sp. MA37
BGC0001869.4	0.41	NRPS, other (phenazine)	griseoluteic acid, demethoxygriseoluteic acid, phenaszentine A, phenaszentine C, phenaszenketide C, phenaszenketide D	Xenorhabdus szentirmaii DSM 16338

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001440.5	1.00	other (other)	cystargolide A, cystargolide B	Kitasatospora cystarginea
BGC0001441.5	0.48	other (other)	belactosin A, belactosin C	Streptomyces sp.
BGC0002554.2	0.43	other (other)	carquinostatin A, carquinostatin B	Streptomyces exfoliatus
BGC0001948.3	0.43	other (other)	naseseazine C, C3-aryl pyrroloindolines	Streptomyces sp.
BGC0002711.2	0.42	PKS	nostovalerolactone, 9-dehydronostovalerolactone	Nostoc punctiforme PCC 73102
BGC0001895.4	0.42	PKS	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001
BGC0001080.5	0.41	other (phenazine)	endophenazine A, endophenazine B	Streptomyces anulatus
BGC0000131.5	0.41	PKS	pyrrolomycin	Streptomyces sp. UC 11065
BGC0001903.3	0.41	other (other)	neocarazostatin A	Streptomyces sp. MA37
BGC0001869.4	0.41	NRPS, other (phenazine)	griseoluteic acid, demethoxygriseoluteic acid, phenaszentine A, phenaszentine C, phenaszenketide C, phenaszenketide D	Xenorhabdus szentirmaii DSM 16338

Similar known clusters from MIBiG 4.0