BGC0001512: BE-24566B biosynthetic gene cluster from Streptomyces sp.
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Location: 50 - 19,375 nt. (total: 19,326 nt).
This entry is originally from NCBI GenBank KY964612.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001512
Short description BE-24566B biosynthetic gene cluster from Streptomyces sp.
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
KY964612.1
50 - 19375
via
Compounds
  • BE-24566B
Species Streptomyces sp. [taxonomy]
References
Chemical products information
BE-24566B Evidence:
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C27H24O7
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AUI41020.1
  • abxN
 50 - 1105 (-) methyltransferase protein
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    • AUI41021.1
    • abxR1
    		 1068 - 1811 (-) transcriptional regulator TetR family
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      • AUI41022.1
      • abxA
      		 1860 - 3374 (+) MFS transporter
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        • AUI41023.1
        • abxO
        		 3525 - 4232 (+) WhiE ORF I SchA/CurD like domain protein
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          • AUI41024.1
          • abxR
          		 4229 - 4630 (+) polyketide WhiE II
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            • AUI41025.1
            • abxP
            		 4666 - 5892 (+) putative polyketide beta-ketoacyl synthase alpha
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              • AUI41026.1
              • abxK
              		 5895 - 7142 (+) keto-acyl synthase beta
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                • AUI41027.1
                • abxS
                		 7179 - 7418 (+) putative acyl carrier protein
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                  • AUI41028.1
                  • abxC
                  		 7415 - 7906 (+) polyketide cyclase
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                    • AUI41029.1
                    • abxD
                    		 7903 - 8244 (+) cyclase
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                      • AUI41030.1
                      • abxH
                      		 8287 - 9564 (+) halogenase
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                        • AUI41031.1
                        • abxB
                        		 9573 - 10904 (+) potassium transporter
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                          • AUI41032.1
                          • abxE
                          		 10816 - 11586 (+) 3-oxoacyl-(acyl-carrier protein) reductase
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                            • AUI41033.1
                            • abxM
                            		 11661 - 12695 (+) O-methyltransferase
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                              • AUI41034.1
                              • abxF
                              		 12838 - 13566 (-) glyoxalase
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                                • AUI41035.1
                                • abxG
                                		 13637 - 15220 (-) MFS transporter
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                                  • AUI41036.1
                                  • abxI
                                  		 15301 - 15873 (+) TetR family transcriptional regulator
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                                    • AUI41037.1
                                    • abxJ
                                    		 16215 - 16964 (+) methyltransferase
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                                      • AUI41038.1
                                      • AbxL
                                      		 16964 - 18616 (+) FAD-dependent monooxygenase
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                                        • AUI41039.1
                                        • abxQ
                                        		 18641 - 19375 (-) methyltransferase
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                                          Biosynthesis information
                                          Annotation changelog

                                          Entry version: 4

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2022-10-07
                                          Update chemical activity to schema version 2.11
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 3

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2022-09-15
                                          Updated bioactivity data
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 2

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2019-10-16
                                          Migrated from v1.4
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          2019-10-16
                                          Updated compound(s) information (NPAtlas curation)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                          Entry version: 1

                                          Date
                                          Changes
                                          Submitters
                                          Reviewers
                                          2018-08-06
                                          Submitted
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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