BGC0001537: butyrolactol A biosynthetic gene cluster from Streptomyces sp. NBRC 110030
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Location: 7,976 - 76,904 nt. (total: 68,929 nt).
This entry is originally from NCBI GenBank NZ_BBOK01000014.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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General
Compounds
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Biosynthesis
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001537
Short description butyrolactol A biosynthetic gene cluster from Streptomyces sp. NBRC 110030
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
NZ_BBOK01000014.1
7976 - 76904
via
Compounds
  • butyrolactol A
Species Streptomyces sp. NBRC 110030 [taxonomy]
References
Chemical products information
butyrolactol A Evidence:
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C28H46O9
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • APK71_RS29920
  • WP_234353270.1
 7976 - 26161 (-) type I polyketide synthase
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    • APK71_RS29925
    • WP_055469546.1
    		 26226 - 27647 (-) carboxyl transferase domain-containing protein
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      • APK71_RS29930
      • WP_055469547.1
      		 28201 - 30231 (+) helix-turn-helix transcriptional regulator
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        • APK71_RS29935
        • WP_234353271.1
        		 30371 - 36634 (+) type I polyketide synthase
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          • APK71_RS29940
          • WP_055469548.1
          		 36682 - 46779 (+) type I polyketide synthase
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            • APK71_RS29945
            • WP_055469549.1
            		 46799 - 57187 (+) type I polyketide synthase
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              • APK71_RS29950
              • WP_055469550.1
              		 57184 - 66591 (+) type I polyketide synthase
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                • APK71_RS29955
                • WP_055469551.1
                		 66588 - 70097 (+) SDR family NAD(P)-dependent oxidoreductase
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                  • APK71_RS29960
                  • WP_055469552.1
                  		 70094 - 70999 (+) 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein
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                    • APK71_RS29965
                    • WP_030403675.1
                    		 71014 - 71280 (+) acyl carrier protein
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                      • APK71_RS29970
                      • WP_055469553.1
                      		 71289 - 72434 (+) acyl-CoA dehydrogenase family protein
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                        • APK71_RS29975
                        • WP_055469554.1
                        		 72431 - 73501 (+) HAD-IIIC family phosphatase
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                          • APK71_RS29980
                          • WP_030403672.1
                          		 73521 - 74306 (+) alpha/beta fold hydrolase
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                            • APK71_RS29985
                            • WP_055469555.1
                            		 74312 - 75658 (+) MFS transporter
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                              • APK71_RS29990
                              • WP_055469556.1
                              		 75651 - 76904 (+) hypothetical protein
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                                Biosynthesis information
                                Annotation changelog

                                Entry version: 4

                                Date
                                Changes
                                Submitters
                                Reviewers
                                2022-10-07
                                Update chemical activity to schema version 2.11
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                Entry version: 3

                                Date
                                Changes
                                Submitters
                                Reviewers
                                2022-09-15
                                Updated bioactivity data
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                Entry version: 2

                                Date
                                Changes
                                Submitters
                                Reviewers
                                2019-10-16
                                Migrated from v1.4
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                2019-10-16
                                Updated compound(s) information (NPAtlas curation)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                Entry version: 1

                                Date
                                Changes
                                Submitters
                                Reviewers
                                2018-08-06
                                Submitted
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                Detailed domain annotation
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