BGC0001556: combamide biosynthetic gene cluster from Streptomyces sp.
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Location: 1 - 21,510 nt. (total: 21,510 nt).
This entry is originally from NCBI GenBank MH167394.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001556
Short description combamide biosynthetic gene cluster from Streptomyces sp.
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
MH167394.1
via
Compounds
  • combamide
Species Streptomyces sp. [taxonomy]
References
Chemical products information
combamide Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AWO77085.1
 569 - 1234 (+) hypothetical protein
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    • AWO77086.1
    		 1424 - 2302 (-) oxidoreductase
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      • AWO77087.1
      • cbmE
      		 2824 - 3657 (+) sterol desaturase family protein
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        • AWO77084.1
        • cbmA
        		 3775 - 13779 (+) hybrid non-ribosomal peptide synthetase/type I polyketide synthase
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          • AWO77088.1
          • cbmB
          		 13769 - 15433 (+) NAD(P)/FAD-dependent oxidoreductase
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            • AWO77089.1
            • cbmC
            		 15445 - 17178 (+) NAD(P)/FAD-dependent oxidoreductase
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              • AWO77090.1
              • cbmD
              		 17132 - 18328 (+) cytochrome P450
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                • AWO77092.1
                		 18984 - 19667 (+) GntR family transcriptional regulator
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                  • AWO77091.1
                  		 19869 - 21149 (-) MFS transporter
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                    Biosynthesis information
                    Annotation changelog

                    Entry version: 4

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2022-10-07
                    Update chemical activity to schema version 2.11
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 3

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2022-09-15
                    Updated bioactivity data
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 2

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2019-10-16
                    Migrated from v1.4
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 1

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2018-08-06
                    Submitted
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    Detailed domain annotation
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