BGC0001567: cysteoamide biosynthetic gene cluster from Streptomyces lincolnensis
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Location: 880,171 - 911,036 nt. (total: 30,866 nt).
This entry is originally from NCBI GenBank CP016438.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001567
Short description cysteoamide biosynthetic gene cluster from Streptomyces lincolnensis
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
CP016438.1
880171 - 911036
via
Compounds
  • cysteoamide
Species Streptomyces lincolnensis [taxonomy]
References
Chemical products information
cysteoamide Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • SLINC_0739
  • ANS62963.1
 880171 - 881904 (-) glycosyl hydrolase
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    • SLINC_0740
    • ANS62964.1
    		 881983 - 883224 (-) putative cytochrome P450
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      • SLINC_0741
      • ANS62965.1
      		 883232 - 883444 (-) hypothetical protein
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        • SLINC_0742
        • ANS62966.1
        		 883441 - 887517 (-) non-ribosomal peptide synthetase
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          • SLINC_0743
          • ANS62967.1
          		 887558 - 895291 (-) non-ribosomal peptide synthase/amino acid adenylation enzyme
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            • SLINC_0744
            • ANS62968.1
            		 895298 - 902947 (-) actinomycin synthetase II
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              • SLINC_0745
              • ANS62969.1
              		 902944 - 904248 (-) L-threonine synthase
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                • SLINC_0746
                • ANS62970.1
                		 904716 - 905666 (+) pyruvate dehydrogenase
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                  • SLINC_0747
                  • ANS62971.1
                  		 905668 - 907680 (+) hypothetical protein
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                    • SLINC_0748
                    • ANS62972.1
                    		 907684 - 909312 (-) integral membrane protein
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                      • SLINC_0749
                      • ANS62973.1
                      		 909591 - 911036 (+) argininosuccinate synthase
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                        Biosynthesis information

                        Biosynthetic modules

                        Name
                        Unk01
                        Type
                        nrps-type1
                        Genes
                        SLINC_0743
                        Substrates
                        valine (evidence: Structure-based inference, Sequence-based prediction)
                        Integrated Monomers
                        Domains
                        adenylation
                        Name
                        Unk02
                        Type
                        nrps-type1
                        Genes
                        SLINC_0743
                        Substrates
                        lysine (evidence: Structure-based inference, Sequence-based prediction)
                        Integrated Monomers
                        Domains
                        adenylation
                        Name
                        Unk03
                        Type
                        nrps-type1
                        Genes
                        SLINC_0742
                        Substrates
                        threonine (evidence: Structure-based inference, Sequence-based prediction)
                        Integrated Monomers
                        Domains
                        adenylation
                        Name
                        Unk04
                        Type
                        nrps-type1
                        Genes
                        SLINC_0744
                        Substrates
                        valine (evidence: Structure-based inference, Sequence-based prediction)
                        Integrated Monomers
                        Domains
                        adenylation
                        Name
                        Unk05
                        Type
                        nrps-type1
                        Genes
                        SLINC_0744
                        Substrates
                        aspartic acid (evidence: Structure-based inference, Sequence-based prediction)
                        Integrated Monomers
                        Domains
                        adenylation
                        Annotation changelog

                        Entry version: 3

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2022-09-15
                        Added NRP substrate specificities
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        2022-09-15
                        Switch to GenBank accessions
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                        Entry version: 2

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2019-10-16
                        Migrated from v1.4
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                        Entry version: 1

                        Date
                        Changes
                        Submitters
                        Reviewers
                        2018-08-06
                        Submitted
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                        Detailed domain annotation
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