BGC0001662 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001662 (Kitasatospora mediocidica)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	161,503	mediomiycin A	Polyketide	100%

BGC0001662 - Region 1 - T1PKS

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Location: 1 - 161,503 nt. (total: 161,503 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 161,504
Label		BGC0001662

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001662.1	0.81	Polyketide	mediomycin A	Kitasatospora mediocidica
BGC0001932.1	0.81	Polyketide	mediomiycin A	Kitasatospora mediocidica
BGC0002072.1	0.34	Polyketide	linearmycin A, linearmycin B, linearmycin C	Streptomyces sp. Mg1
BGC0000041.1	0.34	Polyketide	oronofacic acid	Pseudomonas syringae
BGC0001647.1	0.33	Polyketide	lagunapyrone A, lagunapyrone B, lagunapyrone C	Streptomyces sp. MP131-18
BGC0001273.1	0.31	Polyketide	asperlactone	Aspergillus ochraceus
BGC0001275.1	0.31	Polyketide	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001276.1	0.31	Polyketide	6-methylsalicyclic acid	Aspergillus terreus
BGC0001244.1	0.30	Polyketide	(-)-Mellein	Parastagonospora nodorum
BGC0000018.1	0.30	Polyketide	angolamycin	Streptomyces eurythermus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001662.1	0.93	Polyketide	mediomycin A	Kitasatospora mediocidica
BGC0001932.1	0.93	Polyketide	mediomiycin A	Kitasatospora mediocidica
BGC0002072.1	0.67	Polyketide	linearmycin A, linearmycin B, linearmycin C	Streptomyces sp. Mg1
BGC0000041.1	0.67	Polyketide	oronofacic acid	Pseudomonas syringae
BGC0001647.1	0.66	Polyketide	lagunapyrone A, lagunapyrone B, lagunapyrone C	Streptomyces sp. MP131-18
BGC0001273.1	0.64	Polyketide	asperlactone	Aspergillus ochraceus
BGC0001275.1	0.64	Polyketide	6-methylsalicyclic acid	Glarea lozoyensis
BGC0001276.1	0.64	Polyketide	6-methylsalicyclic acid	Aspergillus terreus
BGC0001244.1	0.64	Polyketide	(-)-Mellein	Parastagonospora nodorum
BGC0000018.1	0.64	Polyketide	angolamycin	Streptomyces eurythermus

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 161503:

Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:: (ccmal - ohmal - ccmal - ohmal - ccmal) + (Me-ohmal) + (ohmal - ohmal - ccmal - ohmal - ohmal) + (ccmal - ohmal) + (ohmal - ccmal - ccmal) + (ccmal - ccmal - ccmal - ccmal) + (Me-ohmal - Me-ohmal) + (ccmal - redmal - ccmal) + (ccmal - Me-ccmal)
Non-colinear ordering:: cle3 + cle4 + cle1 + cle2 + cle5 + cle6 + cle7 + cle8 + cle9

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

cle1

PKS_AT (670..966): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 83.3%; Methylmalonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 237.3
inactive: 137.8
Methoxymalonyl-CoA: 80.9
Methylmalonyl-CoA: 67.7
Isobutyryl-CoA: 41.9
Propionyl-CoA: 40.8
Acetyl-CoA: 26.7
Benzoyl-CoA: 23.8
Ethylmalonyl-CoA: 22.9
2-Methylbutyryl-CoA: 19.1
trans-1,2-CPDA: 18.2
fatty_acid: 11.2
CHC-CoA: 11.1
3-Methylbutyryl-CoA: 0.0

PKS_AT (2211..2502): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 83.3%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 235.8
inactive: 119.9
Methoxymalonyl-CoA: 67.8
Methylmalonyl-CoA: 60.3
Propionyl-CoA: 43.1
Benzoyl-CoA: 25.2
Isobutyryl-CoA: 23.9
Acetyl-CoA: 22.2
Ethylmalonyl-CoA: 20.8
2-Methylbutyryl-CoA: 19.5
trans-1,2-CPDA: 12.7
CHC-CoA: 12.1
fatty_acid: 9.4
3-Methylbutyryl-CoA: 0.0

PKS_AT (3739..4030): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 83.3%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 233.6
inactive: 122.6
Methoxymalonyl-CoA: 66.8
Methylmalonyl-CoA: 60.8
Propionyl-CoA: 41.0
Isobutyryl-CoA: 24.5
Acetyl-CoA: 24.0
Benzoyl-CoA: 23.6
2-Methylbutyryl-CoA: 18.6
Ethylmalonyl-CoA: 15.6
trans-1,2-CPDA: 13.2
CHC-CoA: 12.2
fatty_acid: 9.3
3-Methylbutyryl-CoA: 0.0

PKS_AT (5516..5807): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 83.3%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 237.4
inactive: 123.4
Methoxymalonyl-CoA: 69.6
Methylmalonyl-CoA: 68.1
Propionyl-CoA: 44.6
Benzoyl-CoA: 26.7
Acetyl-CoA: 26.4
Ethylmalonyl-CoA: 26.1
Isobutyryl-CoA: 21.8
trans-1,2-CPDA: 20.1
2-Methylbutyryl-CoA: 19.3
CHC-CoA: 16.9
fatty_acid: 11.1
3-Methylbutyryl-CoA: 0.0

PKS_AT (7037..7331): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 75.0%; Methylmalonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 227.1
inactive: 106.5
Methylmalonyl-CoA: 68.7
Methoxymalonyl-CoA: 67.7
Isobutyryl-CoA: 39.2
Propionyl-CoA: 38.7
Acetyl-CoA: 31.8
Ethylmalonyl-CoA: 26.2
2-Methylbutyryl-CoA: 24.0
Benzoyl-CoA: 20.2
CHC-CoA: 12.0
trans-1,2-CPDA: 6.7
fatty_acid: 5.8
3-Methylbutyryl-CoA: 2.6

cle2

PKS_AT (571..854): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 91.7%; inactive: 75.0%; 2-Rhyd-Malonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 223.3
inactive: 110.5
Methoxymalonyl-CoA: 70.4
Methylmalonyl-CoA: 61.4
Isobutyryl-CoA: 38.4
Propionyl-CoA: 38.3
Ethylmalonyl-CoA: 26.8
2-Methylbutyryl-CoA: 23.3
Acetyl-CoA: 20.0
Benzoyl-CoA: 16.4
CHC-CoA: 15.3
fatty_acid: 14.1
trans-1,2-CPDA: 11.9
3-Methylbutyryl-CoA: 0.0

PKS_AT (2294..2585): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 79.2%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 243.4
inactive: 116.9
Methoxymalonyl-CoA: 68.9
Methylmalonyl-CoA: 62.3
Propionyl-CoA: 41.4
Benzoyl-CoA: 26.2
Acetyl-CoA: 22.1
Isobutyryl-CoA: 22.0
Ethylmalonyl-CoA: 21.5
2-Methylbutyryl-CoA: 15.8
trans-1,2-CPDA: 14.3
CHC-CoA: 12.7
fatty_acid: 9.5
3-Methylbutyryl-CoA: 0.0

cle3

PKS_AT (567..858): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 91.7%; inactive: 79.2%; 2-Rhyd-Malonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 225.7
inactive: 117.1
Methoxymalonyl-CoA: 63.4
Methylmalonyl-CoA: 62.3
Propionyl-CoA: 46.4
Isobutyryl-CoA: 29.7
2-Methylbutyryl-CoA: 24.8
Acetyl-CoA: 23.0
Ethylmalonyl-CoA: 21.3
Benzoyl-CoA: 19.7
trans-1,2-CPDA: 17.7
fatty_acid: 11.1
CHC-CoA: 10.7
3-Methylbutyryl-CoA: 0.0

PKS_AT (2322..2613): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 91.7%; inactive: 83.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 233.2
inactive: 123.5
Methoxymalonyl-CoA: 64.4
Methylmalonyl-CoA: 62.6
Propionyl-CoA: 45.2
Isobutyryl-CoA: 31.0
Acetyl-CoA: 28.9
Ethylmalonyl-CoA: 24.9
Benzoyl-CoA: 22.2
trans-1,2-CPDA: 21.5
2-Methylbutyryl-CoA: 15.6
CHC-CoA: 15.2
fatty_acid: 13.8
3-Methylbutyryl-CoA: 0.0

PKS_AT (3798..4089): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 79.2%; 2-Rhyd-Malonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 238.9
inactive: 122.5
Methoxymalonyl-CoA: 65.7
Methylmalonyl-CoA: 63.2
Propionyl-CoA: 46.2
Isobutyryl-CoA: 28.5
Ethylmalonyl-CoA: 27.3
Acetyl-CoA: 20.8
2-Methylbutyryl-CoA: 19.1
Benzoyl-CoA: 18.7
CHC-CoA: 15.7
trans-1,2-CPDA: 14.6
fatty_acid: 10.2
3-Methylbutyryl-CoA: 0.0

PKS_AT (5547..5838): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 91.7%; inactive: 83.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 228.3
inactive: 123.0
Methoxymalonyl-CoA: 61.3
Methylmalonyl-CoA: 60.4
Propionyl-CoA: 41.6
Isobutyryl-CoA: 30.5
Acetyl-CoA: 28.7
Ethylmalonyl-CoA: 22.8
Benzoyl-CoA: 22.1
trans-1,2-CPDA: 18.9
fatty_acid: 14.0
2-Methylbutyryl-CoA: 13.9
CHC-CoA: 13.7
3-Methylbutyryl-CoA: 0.0

PKS_AT (7083..7375): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 87.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 243.5
inactive: 123.5
Methoxymalonyl-CoA: 64.6
Methylmalonyl-CoA: 57.1
Propionyl-CoA: 43.2
Isobutyryl-CoA: 30.0
Benzoyl-CoA: 25.5
Acetyl-CoA: 21.9
Ethylmalonyl-CoA: 17.7
2-Methylbutyryl-CoA: 17.6
trans-1,2-CPDA: 12.6
CHC-CoA: 11.2
fatty_acid: 10.1
3-Methylbutyryl-CoA: 0.0

cle4

PKS_AT (565..864): mmal

ATSignature: Methylmalonyl-CoA

Top 3 matches:: Methylmalonyl-CoA: 100.0%; Methoxymalonyl-CoA: 95.8%; Ethylmalonyl-CoA: 91.7%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 220.3
Ethylmalonyl-CoA: 204.6
Methoxymalonyl-CoA: 171.9
2-Methylbutyryl-CoA: 141.5
trans-1,2-CPDA: 122.7
Propionyl-CoA: 102.9
Malonyl-CoA: 99.1
CHC-CoA: 90.9
Isobutyryl-CoA: 88.3
Benzoyl-CoA: 64.1
3-Methylbutyryl-CoA: 61.8
Acetyl-CoA: 50.4
fatty_acid: 38.0
inactive: 31.6

cle5

PKS_AT (568..862): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 83.3%; 2-Rhyd-Malonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 242.6
inactive: 114.4
Methoxymalonyl-CoA: 72.4
Methylmalonyl-CoA: 65.6
Propionyl-CoA: 44.3
2-Methylbutyryl-CoA: 29.5
Ethylmalonyl-CoA: 26.6
Acetyl-CoA: 26.0
Isobutyryl-CoA: 25.4
Benzoyl-CoA: 18.2
CHC-CoA: 14.4
trans-1,2-CPDA: 9.5
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0

PKS_AT (2111..2402): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 87.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 242.2
inactive: 123.3
Methoxymalonyl-CoA: 67.7
Methylmalonyl-CoA: 64.8
Propionyl-CoA: 48.8
Isobutyryl-CoA: 32.8
Ethylmalonyl-CoA: 27.3
2-Methylbutyryl-CoA: 23.8
Benzoyl-CoA: 23.3
Acetyl-CoA: 23.2
trans-1,2-CPDA: 17.5
CHC-CoA: 14.7
fatty_acid: 10.6
3-Methylbutyryl-CoA: 0.0

PKS_AT (3877..4171): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 83.3%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 235.6
inactive: 119.3
Methoxymalonyl-CoA: 70.3
Methylmalonyl-CoA: 65.1
Propionyl-CoA: 46.2
Ethylmalonyl-CoA: 27.2
Acetyl-CoA: 26.9
2-Methylbutyryl-CoA: 26.3
Benzoyl-CoA: 21.9
Isobutyryl-CoA: 21.3
CHC-CoA: 15.7
trans-1,2-CPDA: 14.7
fatty_acid: 8.1
3-Methylbutyryl-CoA: 0.0

cle6

PKS_AT (566..857): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 83.3%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 239.0
inactive: 122.0
Methoxymalonyl-CoA: 70.3
Methylmalonyl-CoA: 68.6
Propionyl-CoA: 47.0
Ethylmalonyl-CoA: 29.9
2-Methylbutyryl-CoA: 28.3
Acetyl-CoA: 26.9
Isobutyryl-CoA: 24.4
Benzoyl-CoA: 22.2
CHC-CoA: 16.3
trans-1,2-CPDA: 14.3
fatty_acid: 9.2
3-Methylbutyryl-CoA: 0.0

PKS_AT (2323..2614): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 83.3%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 239.0
inactive: 124.7
Methoxymalonyl-CoA: 65.8
Methylmalonyl-CoA: 61.5
Propionyl-CoA: 37.4
Isobutyryl-CoA: 22.4
Acetyl-CoA: 21.9
Benzoyl-CoA: 20.9
Ethylmalonyl-CoA: 16.5
CHC-CoA: 12.3
2-Methylbutyryl-CoA: 11.8
trans-1,2-CPDA: 10.7
fatty_acid: 9.1
3-Methylbutyryl-CoA: 0.0

PKS_AT (4076..4366): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 87.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 236.0
inactive: 125.3
Methoxymalonyl-CoA: 67.6
Methylmalonyl-CoA: 60.6
Propionyl-CoA: 43.0
Benzoyl-CoA: 27.1
Isobutyryl-CoA: 26.8
Ethylmalonyl-CoA: 26.4
Acetyl-CoA: 26.4
trans-1,2-CPDA: 20.1
CHC-CoA: 16.4
2-Methylbutyryl-CoA: 16.4
fatty_acid: 10.5
3-Methylbutyryl-CoA: 0.0

PKS_AT (5823..6114): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 83.3%; 2-Rhyd-Malonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 236.4
inactive: 117.5
Methoxymalonyl-CoA: 69.6
Methylmalonyl-CoA: 61.5
Propionyl-CoA: 43.7
Isobutyryl-CoA: 29.5
Acetyl-CoA: 29.1
Ethylmalonyl-CoA: 28.0
Benzoyl-CoA: 25.1
2-Methylbutyryl-CoA: 18.3
trans-1,2-CPDA: 17.3
CHC-CoA: 15.5
fatty_acid: 10.0
3-Methylbutyryl-CoA: 0.0

cle7

PKS_AT (586..885): mmal

ATSignature: Methylmalonyl-CoA

Top 3 matches:: Methylmalonyl-CoA: 100.0%; Methoxymalonyl-CoA: 95.8%; Ethylmalonyl-CoA: 91.7%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 216.8
Ethylmalonyl-CoA: 202.9
Methoxymalonyl-CoA: 168.8
2-Methylbutyryl-CoA: 139.5
trans-1,2-CPDA: 120.3
Propionyl-CoA: 101.4
Isobutyryl-CoA: 92.9
CHC-CoA: 92.9
Malonyl-CoA: 92.3
Benzoyl-CoA: 66.0
3-Methylbutyryl-CoA: 59.9
Acetyl-CoA: 51.4
fatty_acid: 39.4
inactive: 30.2

PKS_AT (2124..2423): mmal

ATSignature: Methylmalonyl-CoA

Top 3 matches:: Methylmalonyl-CoA: 100.0%; Methoxymalonyl-CoA: 95.8%; Ethylmalonyl-CoA: 91.7%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 215.0
Ethylmalonyl-CoA: 205.8
Methoxymalonyl-CoA: 168.4
2-Methylbutyryl-CoA: 144.4
trans-1,2-CPDA: 125.9
Propionyl-CoA: 102.9
Malonyl-CoA: 95.4
CHC-CoA: 93.0
Isobutyryl-CoA: 86.7
Benzoyl-CoA: 66.6
3-Methylbutyryl-CoA: 55.1
Acetyl-CoA: 48.5
fatty_acid: 43.8
inactive: 31.2

cle8

PKS_AT (573..864): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; inactive: 83.3%; 2-Rhyd-Malonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 228.6
inactive: 120.9
Methoxymalonyl-CoA: 68.0
Methylmalonyl-CoA: 61.9
Propionyl-CoA: 40.9
Acetyl-CoA: 31.4
Isobutyryl-CoA: 30.3
Benzoyl-CoA: 28.5
Ethylmalonyl-CoA: 26.4
2-Methylbutyryl-CoA: 23.9
CHC-CoA: 18.6
trans-1,2-CPDA: 17.6
fatty_acid: 16.2
3-Methylbutyryl-CoA: 0.0

PKS_AT (2341..2632): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 79.2%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 237.5
inactive: 118.1
Methoxymalonyl-CoA: 66.3
Methylmalonyl-CoA: 63.7
Propionyl-CoA: 44.6
Benzoyl-CoA: 26.0
Isobutyryl-CoA: 25.3
Ethylmalonyl-CoA: 25.2
Acetyl-CoA: 22.9
2-Methylbutyryl-CoA: 20.7
CHC-CoA: 15.7
trans-1,2-CPDA: 15.1
fatty_acid: 10.5
3-Methylbutyryl-CoA: 0.0

PKS_AT (4420..4710): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 95.8%; inactive: 83.3%; 2-Rhyd-Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 233.3
inactive: 125.4
Methoxymalonyl-CoA: 68.3
Methylmalonyl-CoA: 65.9
Propionyl-CoA: 45.9
Ethylmalonyl-CoA: 32.5
Benzoyl-CoA: 23.4
2-Methylbutyryl-CoA: 22.9
Isobutyryl-CoA: 21.3
Acetyl-CoA: 21.2
CHC-CoA: 16.8
trans-1,2-CPDA: 15.4
fatty_acid: 8.3
3-Methylbutyryl-CoA: 0.0

cle9

PKS_AT (574..864): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 91.7%; inactive: 75.0%; 2-Rhyd-Malonyl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 227.0
inactive: 115.0
Methoxymalonyl-CoA: 63.7
Methylmalonyl-CoA: 63.1
Propionyl-CoA: 47.7
Isobutyryl-CoA: 29.6
Acetyl-CoA: 27.1
2-Methylbutyryl-CoA: 26.8
Benzoyl-CoA: 21.9
trans-1,2-CPDA: 15.1
Ethylmalonyl-CoA: 14.3
CHC-CoA: 11.4
fatty_acid: 8.2
3-Methylbutyryl-CoA: 0.0

PKS_AT (2322..2621): mmal

ATSignature: Methylmalonyl-CoA

Top 3 matches:: Methylmalonyl-CoA: 100.0%; Methoxymalonyl-CoA: 95.8%; Ethylmalonyl-CoA: 91.7%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 220.9
Ethylmalonyl-CoA: 209.6
Methoxymalonyl-CoA: 175.0
2-Methylbutyryl-CoA: 138.9
trans-1,2-CPDA: 126.5
Propionyl-CoA: 102.5
Malonyl-CoA: 93.6
CHC-CoA: 91.2
Isobutyryl-CoA: 86.4
Benzoyl-CoA: 67.4
3-Methylbutyryl-CoA: 64.6
Acetyl-CoA: 49.5
fatty_acid: 41.8
inactive: 32.4

cleG

PKS_AT (11..281): pk

ATSignature: (unknown)

No matches above 50%

minowa: CHC-CoA

Prediction, score:

CHC-CoA: 13.1
trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

cleE

Search NORINE for peptide: strict or relaxed

AMP-binding (9..371): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: qYsdCGsnIK
Nearest Stachelhaus code:: pip
Stachelhaus code match:: 50% (weak)