BGC0001662: mediomycin A biosynthetic gene cluster from Kitasatospora mediocidica
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Location: 6,894 - 168,396 nt. (total: 161,503 nt).
This entry is originally from NCBI GenBank MF139773.1.

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core biosynthetic genes
additional biosynthetic genes
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Gene details
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General
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001662
Short description mediomycin A biosynthetic gene cluster from Kitasatospora mediocidica
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: MF139773.1
Compounds
  • mediomycin A
Species Kitasatospora mediocidica [taxonomy]
References
Chemical products information
mediomycin A
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C62H97N1O18S1
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AWC08646.1
  • cleP
 6894 - 7373 (+) putative transcriptional regulator
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  • AWC08647.1
  • cleO
 7414 - 8199 (-) putative 4-guanidinobutyramide hydrolase
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  • AWC08648.1
  • cleN
 8465 - 9232 (+) putative type II TE
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  • AWC08649.1
  • cleM
 9320 - 12211 (+) putative LuxR-family transcriptional regulator
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  • AWC08650.1
  • cleL
 12250 - 12879 (-) putative two-component system response regulator
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  • AWC08651.1
  • cleK
 12872 - 14125 (-) putative histidine kinase
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  • AWC08652.1
  • cleJ
 14293 - 14826 (+) hypothetical protein
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  • AWC08653.1
  • cleI
 14901 - 15395 (+) putative membrane protein
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  • AWC08654.1
  • cleH
 15392 - 16948 (+) putative membrane protein
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  • AWC08655.1
  • cle1
 17236 - 41595 (+) polyketide synthase type I
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  • AWC08656.1
  • cle2
 41602 - 51735 (+) polyketide synthase type I
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  • AWC08657.1
  • cle3
 51761 - 76960 (+) polyketide synthase type I
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  • AWC08658.1
  • cle4
 77088 - 82043 (+) polyketide synthase type I
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  • AWC08659.1
  • cle5
 82267 - 97758 (+) polyketide synthase type I
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  • AWC08660.1
  • cle6
 97816 - 119211 (+) polyketide synthase type I
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  • AWC08661.1
  • cle7
 119264 - 128902 (+) polyketide synthase type I
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  • AWC08662.1
  • cle8
 128958 - 146066 (+) polyketide synthase type I
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  • AWC08663.1
  • cle9
 146148 - 157649 (+) polyketide synthase type I
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  • AWC08664.1
  • cleG
 157808 - 158752 (-) ACP acyltransferase
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  • AWC08665.1
  • cleF
 159165 - 159836 (+) putative type II TE
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  • AWC08666.1
  • cleE
 159900 - 161306 (+) putative 4-guanidinylbutanoate:CoA ligase
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  • AWC08667.1
  • cleD
 161370 - 163031 (-) putative L-arginine monooxygenase
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  • AWC08668.1
  • cleC
 163133 - 165961 (-) putative LuxR-family transcriptional regulator
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  • AWC08669.1
  • cleB
 166554 - 167603 (+) sulfotransferase
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  • AWC08670.1
  • cleA
 167763 - 168353 (+) hypothetical protein
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Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Merge in annotations from duplicated entry BGC0001932
  • Cleaned up synonym list
Detailed domain annotation
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