BGC0001693: nenestatin biosynthetic gene cluster from Micromonospora echinospora
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Location: 3,153 - 70,000 nt. (total: 66,848 nt).
This entry is originally from NCBI GenBank KY454837.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0001693
Short description nenestatin biosynthetic gene cluster from Micromonospora echinospora
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
KY454837.1
3153 - 68576
via
Compounds
  • nenestatin
Species Micromonospora echinospora [taxonomy]
References
  • [1]
Chemical products information
nenestatin Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ARD70850.1
 3153 - 3635 (+) hypothetical protein
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    • ARD70851.1
    		 3788 - 4618 (-) ABC transporter
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      • ARD70852.1
      		 4615 - 5574 (-) ABC transporter
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        • ARD70853.1
        		 5670 - 6095 (-) glyoxalase/bleomycin resistance
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          • ARD70854.1
          		 6215 - 6991 (-) hypothetical protein
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            • ARD70855.1
            		 7114 - 7926 (-) SARP family regulatory protein
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              • ARD70856.1
              		 9201 - 10049 (+) AraC family transcriptional regulator
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                • ARD70857.1
                		 10479 - 11873 (+) NDP-hexose 2,3 dehydratase
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                  • ARD70858.1
                  		 11953 - 12618 (-) hypothetical protein
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                    • ARD70859.1
                    		 12655 - 13101 (-) carboxymuconolactone decarboxylase
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                      • ARD70860.1
                      		 13171 - 14025 (-) Glutamyl hydrolase, amidotransferase
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                        • ARD70861.1
                        		 14542 - 16191 (+) FAD-binding monooxygenase
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                          • ARD70862.1
                          		 16329 - 17798 (-) Protoporphyrinogen oxidase
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                            • ARD70863.1
                            		 17907 - 18959 (-) Nuclease
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                              • ARD70864.1
                              		 19096 - 20577 (-) FAD-binding monooxygenase
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                                • ARD70865.1
                                		 20574 - 22034 (-) FAD-binding monooxygenase
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                                  • ARD70866.1
                                  		 22272 - 23000 (+) Short-chain dehydrogenase/reductase
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                                    • ARD70867.1
                                    		 23075 - 23920 (+) NmrA family protein
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                                      • ARD70868.1
                                      		 23983 - 24600 (-) DSBA oxidoreductase
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                                        • ARD70869.1
                                        		 24663 - 24992 (-) Polyketide synthesis, cyclase
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                                          • ARD70870.1
                                          		 25036 - 25821 (-) Polyketide synthesis, ketoreductase
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                                            • ARD70871.1
                                            		 26017 - 27054 (+) O-methyltransferase
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                                              • ARD70872.1
                                              		 27109 - 28620 (+) FAD-binding monooxygenase
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                                                • ARD70873.1
                                                		 28647 - 29606 (+) cyclase
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                                                  • ARD70874.1
                                                  		 29603 - 31039 (+) FAD-binding monooxygenase
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                                                    • ARD70875.1
                                                    		 31026 - 32504 (+) FAD-binding monooxygenase
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                                                      • ARD70876.1
                                                      		 32561 - 33304 (+) anthrone oxidase
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                                                        • ARD70877.1
                                                        		 33373 - 35256 (-) hypothetical protein
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                                                          • ARD70878.1
                                                          		 35237 - 35593 (-) 4Fe-4S ferredoxin
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                                                            • ARD70879.1
                                                            		 35668 - 36462 (-) hypothetical protein
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                                                              • ARD70880.1
                                                              		 36499 - 37992 (-) glutamine synthase
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                                                                • ARD70881.1
                                                                		 37995 - 39413 (-) amidase
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                                                                  • ARD70882.1
                                                                  		 39624 - 40910 (+) adenylosuccinate lyase
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                                                                    • ARD70883.1
                                                                    		 40894 - 41295 (+) N-acetyltransferase
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                                                                      • ARD70884.1
                                                                      		 41406 - 43172 (-) ABC transporter
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                                                                        • ARD70885.1
                                                                        		 43575 - 43904 (-) Rieske (2Fe-2S) domain protein
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                                                                          • ARD70886.1
                                                                          		 44148 - 44558 (+) glyoxalase
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                                                                            • ARD70887.1
                                                                            		 44642 - 45442 (+) glyoxalase
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                                                                              • ARD70888.1
                                                                              		 45500 - 47050 (-) secreted peptidase
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                                                                                • ARD70889.1
                                                                                		 47571 - 48692 (-) glycosyltransferase
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                                                                                  • ARD70890.1
                                                                                  		 48689 - 49708 (-) O-methyltransferase
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                                                                                    • ARD70891.1
                                                                                    		 50074 - 51006 (+) N-methyltransferase
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                                                                                      • ARD70892.1
                                                                                      		 51054 - 52055 (+) NAD-dependent epimerase/dehydratase
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                                                                                        • ARD70893.1
                                                                                        		 52042 - 52767 (+) methyltransferase
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                                                                                          • ARD70894.1
                                                                                          		 52764 - 53873 (+) aminotransferase
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                                                                                            • ARD70895.1
                                                                                            		 53897 - 54508 (+) NDP-4-keto-6-deoxyhexose 3,5-epimerase
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                                                                                              • ARD70896.1
                                                                                              		 54685 - 55680 (+) NDP-hexose-3-ketoreductase
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                                                                                                • ARD70897.1
                                                                                                		 55735 - 56451 (-) hypothetical protein
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                                                                                                  • ARD70898.1
                                                                                                  		 56544 - 57596 (-) glycosyltransferase
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                                                                                                    • ARD70899.1
                                                                                                    		 57789 - 59009 (-) deoxysugar aminotransferase
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                                                                                                      • ARD70900.1
                                                                                                      		 59205 - 60278 (+) dTDP-glucose 4,6-dehydratase
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                                                                                                        • ARD70901.1
                                                                                                        		 60275 - 61546 (+) beta-ketoacyl synthase
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                                                                                                          • ARD70902.1
                                                                                                          		 61543 - 62841 (+) chain length factor
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                                                                                                            • ARD70903.1
                                                                                                            		 62829 - 63083 (+) acyl carrier protein
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                                                                                                              • ARD70904.1
                                                                                                              		 63065 - 64102 (+) acyltransferase
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                                                                                                                • ARD70905.1
                                                                                                                		 64219 - 65196 (+) acyltransferase/decarboxylase
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                                                                                                                  • ARD70906.1
                                                                                                                  		 65225 - 65554 (-) acyl carrier protein
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                                                                                                                    • ARD70907.1
                                                                                                                    		 65681 - 66136 (+) transcriptional regulator
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                                                                                                                      • ARD70908.1
                                                                                                                      		 66215 - 67639 (+) propionyl-CoA carboxylase subunit beta
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                                                                                                                        • ARD70909.1
                                                                                                                        		 67704 - 68576 (+) dTDP-1-glucose synthase
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                                                                                                                          Biosynthesis information

                                                                                                                          No biosynthesis information available for this record.

                                                                                                                          Annotation changelog

                                                                                                                          Entry version: 2

                                                                                                                          Date
                                                                                                                          Changes
                                                                                                                          Submitters
                                                                                                                          Reviewers
                                                                                                                          2019-10-16
                                                                                                                          Migrated from v1.4
                                                                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                                                          Entry version: 1

                                                                                                                          Date
                                                                                                                          Changes
                                                                                                                          Submitters
                                                                                                                          Reviewers
                                                                                                                          2018-08-06
                                                                                                                          Submitted
                                                                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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