Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001701.1:
Cluster 1RiPP116220

BGC0001701, nisin O biosynthetic gene cluster from Blautia obeum. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: nisin O

Class-specific details

Biosynthetic class(es):
RiPP

Gene cluster description

nisin O (BGC0001701). Gene Cluster 1. Biosynthetic class = RiPP. GenBank KY914474. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

nsoA1 leader / core peptide, putative Class I
MGKFDDFDLDVTKTAAQGGIEPK - YKDhaKDhaACDhbPGCPDhbGILMDhbCPLKDhbADhbCGCHIDhbGK
nsoA2 leader / core peptide, putative Class I
MAKFDDFDLDVTKTAAQGGIEPK - YKDhaKDhaACDhbPGCPDhbGILMDhbCPLKDhbADhbCGCHIDhbGK
nsoA3 leader / core peptide, putative Class I
MAKFDDFDLDVTKTAAQGGIEPK - YKDhaKDhaACDhbPGCPDhbGILMDhbCPLKDhbADhbCGCHIDhbGK
nsoA4 leader / core peptide, putative Class I
MAKFDDFDLDIIEKKVRRDIIPA - DhaIDhbDhaQHDhaFCDhbPNCLDhbGFLCPPKDhbQLDhbCDhbCKLKGQ

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Homologous known gene clusters

Literature references

1. Hatziioanou D et al. (2017) Discovery of a novel lantibiotic nisin O from Blautia obeum A2-162, isolated from the human gastrointestinal tract. Microbiology 163(9):1292-1305. doi: 10.1099/mic.0.000515. Epub 2017 Aug