BGC0001749 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001749 (Pyricularia oryzae 70-15)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	54,985	neurosporin A	Polyketide	53%

BGC0001749 - Region 1 - T1PKS

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Location: 1 - 54,985 nt. (total: 54,985 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 54,986
Label		BGC0001749

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001749.1	0.62	Polyketide	epipyriculol	Pyricularia oryzae 70-15
BGC0001280.1	0.25	Polyketide	betaenone C, betaenone A	Phoma betae
BGC0001264.1	0.25	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0001068.1	0.25	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0000056.1	0.23	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0001254.1	0.22	Polyketide	ACT-Toxin II	Alternaria alternata
BGC0000003.1	0.21	Polyketide	AF-toxin	Alternaria alternata
BGC0001141.1	0.21	Polyketide	4-epi-15-epi-brefeldin A	Penicillium brefeldianum
BGC0000121.1	0.21	Polyketide	RES-1214-2	Pestalotiopsis fici
BGC0001284.1	0.21	Terpene	alternariol	Parastagonospora nodorum SN15

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001749.1	0.87	Polyketide	epipyriculol	Pyricularia oryzae 70-15
BGC0001280.1	0.58	Polyketide	betaenone C, betaenone A	Phoma betae
BGC0001264.1	0.58	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0001068.1	0.58	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0000056.1	0.56	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0001254.1	0.55	Polyketide	ACT-Toxin II	Alternaria alternata
BGC0000003.1	0.54	Polyketide	AF-toxin	Alternaria alternata
BGC0001141.1	0.54	Polyketide	4-epi-15-epi-brefeldin A	Penicillium brefeldianum
BGC0000121.1	0.54	Polyketide	RES-1214-2	Pestalotiopsis fici
BGC0001284.1	0.54	Terpene	alternariol	Parastagonospora nodorum SN15

Similar known gene clusters

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 4780 - 52566:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

MGG_10912

PKS_AT (608..923): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 62.5%; Isobutyryl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 60.4
Methoxymalonyl-CoA: 52.0
Malonyl-CoA: 47.0
Propionyl-CoA: 19.9
Benzoyl-CoA: 19.9
fatty_acid: 11.4
Isobutyryl-CoA: 10.8
CHC-CoA: 8.5
2-Methylbutyryl-CoA: 3.8
trans-1,2-CPDA: 0.0
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
Ethylmalonyl-CoA: -2.0