Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001753.1:
Cluster 1RiPP120652

BGC0001753, radamycin / globimycin biosynthetic gene cluster from Streptomyces globisporus. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: radamycin
SMILES string: Copy to clipboard

Class-specific details

Biosynthetic class(es):
RiPP

Gene cluster description

radamycin / globimycin (BGC0001753). Gene Cluster 1. Biosynthetic class = RiPP. GenBank NZ_JNZK01000003, positions 134923-155574. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Detailed annotation

IF53_RS1000000135460 leader / core peptide, putative Class I
MDAVESLDLNALEISDLIEDSNYSDETLSQA - MAADhaDhbDhbDhbDhbGCDhbDhbDhaDhaCDhaDhaDhaDhaDha
IF53_RS1000000135465 leader / core peptide, putative Class I
MNSSEELDLNALEISDLIDELGRDNETLSQ - VMAADhaCVGDhbACACDhaDhaDhbDhaDhaDhaDha

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Homologous known gene clusters

Literature references

1. Issara Kaweewan, Hisayuki Komaki, Hikaru Hemmi, Shinya Kodani. (2018) Isolation and structure determination of a new thiopeptide globimycin from Streptomyces globisporus subsp. globisporus based on genome mining. Tetrahedron Letters, vol. 59, no. 4, pp. 409-414