BGC0001762: rubrolone A biosynthetic gene cluster from Streptomyces sp. KIB-H033
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Location: 1 - 36,216 nt. (total: 36,216 nt).
This entry is originally from NCBI GenBank KX218108.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
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KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001762
Short description rubrolone A biosynthetic gene cluster from Streptomyces sp. KIB-H033
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
Loci
KX218108.1
via
Compounds
  • rubrolone A
  • rubrolone B
Species Streptomyces sp. KIB-H033 [taxonomy]
References
Chemical products information
rubrolone A Evidence: NMR [1]
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Chemical database entries
PubCHEM
rubrolone B Evidence: NMR [1]
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Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AOZ61185.1
 1 - 1356 (+) amidohydrolase
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    • AOZ61186.1
    		 1411 - 1920 (-) marR family transcriptional regulator
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      • AOZ61187.1
      		 2048 - 3112 (+) hypothetical protein
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        • AOZ61188.1
        		 3203 - 4120 (-) transposase
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          • AOZ61189.1
          		 4159 - 4557 (-) hypothetical protein
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            • AOZ61190.1
            		 4617 - 5012 (+) hypothetical protein
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              • AOZ61191.1
              		 5013 - 5951 (-) zinc-containing alcohol dehydrogenase
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                • AOZ61192.1
                • rubS1
                		 6260 - 7738 (+) FAD-linked oxidoreductase
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                  • AOZ61193.1
                  • rubN1
                  		 7735 - 8142 (+) hypothetical protein
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                    • AOZ61194.1
                    • rubS2
                    		 8255 - 8869 (+) dTDP-4-keto-6-deoxy-D-glucose 3,5-epimerase
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                      • AOZ61195.1
                      • rubS3
                      		 9005 - 9937 (-) dTDP-glucose-4-ketoreductase
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                        • AOZ61196.1
                        • rubS4
                        		 9934 - 10965 (-) dTDP-glucose 4,6 dehydratase
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                          • AOZ61197.1
                          • rubS5
                          		 10982 - 11851 (-) Glucose-1-phosphate thymidylyltransferase
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                            • AOZ61198.1
                            • rubS6
                            		 11873 - 12709 (-) NAD dependent epimerase/dehydratase
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                              • AOZ61199.1
                              • rubS7
                              		 12820 - 13974 (-) Glycosyltransferase
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                                • AOZ61200.1
                                • rubR
                                		 14184 - 15221 (-) SARP family transcriptional regulator
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                                  • AOZ61201.1
                                  • rubN2
                                  		 15281 - 15628 (-) hypothetical protein
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                                    • AOZ61202.1
                                    • rubA
                                    		 16270 - 17205 (+) F420-dependent oxidoreductase
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                                      • AOZ61203.1
                                      • rubB
                                      		 17783 - 19339 (+) oxygenase
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                                        • AOZ61204.1
                                        • rubC
                                        		 19336 - 20505 (+) naphthocyclinone hydroxylase
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                                          • AOZ61205.1
                                          • rubE1
                                          		 20878 - 21837 (-) ketoacylsynthase III
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                                            • AOZ61206.1
                                            • rubE2
                                            		 22119 - 22394 (+) acyl carrier protein
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                                              • AOZ61207.1
                                              • rubE3
                                              		 22549 - 23469 (+) acyl transferase
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                                                • AOZ61208.1
                                                • rubE4
                                                		 23539 - 23793 (+) acyl carrier protein
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                                                  • AOZ61209.1
                                                  • rubE5
                                                  		 24233 - 24727 (+) bifunctional cyclase/dehydratase
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                                                    • AOZ61210.1
                                                    • rubE6
                                                    		 24727 - 25482 (+) cyclase
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                                                      • AOZ61211.1
                                                      • rubE7
                                                      		 25479 - 26099 (+) NADH dehydrogenase/NADPH nitroreductase
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                                                        • AOZ61212.1
                                                        • rubE8
                                                        		 26249 - 27478 (+) beta-ketoacylsynthase I
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                                                          • AOZ61213.1
                                                          • rubE9
                                                          		 27508 - 28710 (+) chain length factor
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                                                            • AOZ61214.1
                                                            		 28805 - 29917 (-) Isopentenyl-diphosphate delta-isomerase
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                                                              • AOZ61216.1
                                                              		 30185 - 30424 (-) hypothetical protein
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                                                                • AOZ61215.1
                                                                		 30410 - 31942 (+) methylmalonyl-CoA decarboxylase subunit alpha
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                                                                  • AOZ61217.1
                                                                  		 32690 - 33895 (+) 3-oxoadipate enol-lactonase
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                                                                    • AOZ61218.1
                                                                    		 34034 - 34678 (+) metallo-beta-lactamase domain protein
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                                                                      • AOZ61219.1
                                                                      		 34772 - 35551 (+) exodeoxyribonuclease III
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                                                                        • AOZ61220.1
                                                                        		 35770 - 36216 (+) hypothetical protein
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                                                                          Biosynthesis information
                                                                          Annotation changelog

                                                                          Entry version: next

                                                                          Date
                                                                          Changes
                                                                          Submitters
                                                                          Reviewers
                                                                          2024-05-14
                                                                          MIBiG v4 annotathon
                                                                          • (ID: SJG3CBEHSM6A3I74YXLH6GLA)
                                                                          • (ID: U45G63MLSP33JST2JZS23R4V)
                                                                          • (ID: 3NQIBNAT6ZIBJV3NZKMFJFBW)
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                          Entry version: 2

                                                                          Date
                                                                          Changes
                                                                          Submitters
                                                                          Reviewers
                                                                          2019-10-16
                                                                          Migrated from v1.4
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                          Entry version: 1

                                                                          Date
                                                                          Changes
                                                                          Submitters
                                                                          Reviewers
                                                                          2018-08-06
                                                                          Submitted
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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