BGC0001762 - 1 region(s) - antiSMASH results

BGC0001762 (Streptomyces sp. KIB-H033)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T2PKS	1	36,216	isatropolone A / isotropolone B / isotropolone C	Polyketide	61%

BGC0001762 - Region 1 - T2PKS

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Location: 1 - 36,216 nt. (total: 36,216 nt) Show pHMM detection rules used

Region on contig edge.

T2PKS: (t2ks and t2clf)

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

External annotation

Name		MIBiG
Version		3.0

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001762.1	1.00	Alkaloid	rubrolone A, rubrolone B	Streptomyces sp. KIB-H033
BGC0000248.1	0.40	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000228.1	0.30	Polyketide	granaticin	Streptomyces violaceoruber
BGC0000272.1	0.27	Polyketide	spore pigment	Streptomyces collinus
BGC0001104.1	0.25	NRP, Polyketide	myxovirescin A1	Myxococcus xanthus DK 1622
BGC0001903.1	0.25	Other	neocarazostatin A	Streptomyces sp. MA37
BGC0000231.1	0.25	Polyketide	griseusin	Streptomyces griseus
BGC0001797.1	0.25	RiPP	telomestatin	Streptomyces anulatus
BGC0000215.1	0.25	Polyketide	curamycin	Streptomyces cyaneus
BGC0000271.1	0.23	Polyketide	spore pigment	Streptomyces avermitilis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001762.1	1.00	Alkaloid	rubrolone A, rubrolone B	Streptomyces sp. KIB-H033
BGC0000248.1	0.72	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000228.1	0.64	Polyketide	granaticin	Streptomyces violaceoruber
BGC0000272.1	0.61	Polyketide	spore pigment	Streptomyces collinus
BGC0001104.1	0.59	NRP, Polyketide	myxovirescin A1	Myxococcus xanthus DK 1622
BGC0001903.1	0.59	Other	neocarazostatin A	Streptomyces sp. MA37
BGC0000231.1	0.59	Polyketide	griseusin	Streptomyces griseus
BGC0001797.1	0.58	RiPP	telomestatin	Streptomyces anulatus
BGC0000215.1	0.58	Polyketide	curamycin	Streptomyces cyaneus
BGC0000271.1	0.56	Polyketide	spore pigment	Streptomyces avermitilis

Similar known gene clusters

Type II PKS

Type II PKS gene cluster prediction details

Cluster section:: 0 to 36216
Starter unit(s):: butyryl-CoA (Score: 480.2; E-value: 1.23e-147)
acetyl-CoA (Score: 71.2; E-value: 1.64e-98)
propionyl-CoA (Score: 71.2; E-value: 1.64e-98)
isobutyryl-CoA (Score: 71.2; E-value: 1.64e-98)
Malonyl elongations:: 7 (Score: 698.9; E-value: 4.1e-213)
Product molecular weight(s):: acetyl-CoA_7: 485.46 Da
butyryl-CoA_7: 513.51 Da
isobutyryl-CoA_7: 513.51 Da
propionyl-CoA_7: 499.49 Da

rubB: OXY (Score: 435.2; E-value: 7.8e-133)
rubE1: KSIII (Score: 367.9; E-value: 1.1e-112); KSIII BAJ52704.1_FD-594_butyryl-CoA (Score: 409.0; E-value: 1.23e-147)
rubE2: ACP (Score: 71.4; E-value: 1.1e-22)
rubE3: AT (Score: 392.3; E-value: 4.1e-120); AT AAG30190.1_R1128_acetyl-CoA/propionyl-CoA/isobutyryl-CoA/butyryl-CoA (Score: 285.0; E-value: 1.64e-98)
rubE4: ACP (Score: 109.4; E-value: 1.5e-34)
rubE5: CYC C7-C12 (Score: 131.5; E-value: 6.9e-41)
rubE6: CYC C5-C14/C3-C16 (Score: 333.8; E-value: 1.6e-102)
rubE8: KS (Score: 755.7; E-value: 2.7e-230)
rubE9: CLF 7 (Score: 698.9; E-value: 4.1e-213)
rubS7: GT (Score: 321.0; E-value: 3.3e-98)