BGC0001771 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001771 (Streptomyces sclerotialus)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS,butyrolactone	1	18,478	scleric acid	NRPS:Type I	100%

BGC0001771 - Region 1 - NRPS,butyrolactone

Download region GenBank file

Download region SVG

Location: 1 - 18,478 nt. (total: 18,478 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
butyrolactone: AfsA

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 18,479
Label		BGC0001771

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001771	1.36	NRP	scleric acid	Streptomyces sclerotialus
BGC0000850	0.69	Other	γ-butyrolactone	Streptomyces acidiscabies
BGC0001736	0.67	NRP	pepteridine A, pepteridine B	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000849	0.63	Other (Butyrolactone)	SCB1, SCB2, SCB3	Streptomyces coelicolor A3(2)
BGC0002578	0.58	Other	gaburedin A, gaburedin B, gaburedin C, gaburedin D, gaburedin E, gaburedin F	Streptomyces venezuelae ATCC 10712
BGC0001487	0.36	Other	3,7-dihydroxytropolone	Streptomyces cyaneofuscatus
BGC0000343	0.33	NRP	enterobactin	Pseudomonas sp. J465
BGC0002474	0.32	NRP	agrobactin	Agrobacterium tumefaciens
BGC0001625	0.32	Polyketide	isofuranonaphthoquinone	Streptomyces sp. CB01883
BGC0000914	0.31	Other	methylenomycin A	Streptomyces coelicolor A3(2)

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001771	1.00	NRP	scleric acid	Streptomyces sclerotialus
BGC0001736	0.70	NRP	pepteridine A, pepteridine B	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001487	0.69	Other	3,7-dihydroxytropolone	Streptomyces cyaneofuscatus
BGC0000850	0.68	Other	γ-butyrolactone	Streptomyces acidiscabies
BGC0000343	0.66	NRP	enterobactin	Pseudomonas sp. J465
BGC0002474	0.66	NRP	agrobactin	Agrobacterium tumefaciens
BGC0000849	0.65	Other (Butyrolactone)	SCB1, SCB2, SCB3	Streptomyces coelicolor A3(2)
BGC0002578	0.65	Other	gaburedin A, gaburedin B, gaburedin C, gaburedin D, gaburedin E, gaburedin F	Streptomyces venezuelae ATCC 10712
BGC0002493	0.64	NRP	parabactin	Paracoccus denitrificans PD1222
BGC0002476	0.61	NRP	enterobactin	Escherichia coli str. K-12 substr. MG1655

Similar known gene clusters from MIBiG 4.0

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 18478:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Pro)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

IG96_RS37880

Search NORINE for peptide: strict or relaxed

AMP-binding (463..859): Pro

nrpys: Pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Cyclic aliphatic chain (polar NH2 group) (Pro, Hpr)
Small clusters prediction:: pro (Pro)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVQYCAMVVK
Nearest Stachelhaus code(s):: Pro DVQYCAMVVK (100% 8Å match)
Stachelhaus code match:: 100% (strong)