BGC0001771: scleric acid biosynthetic gene cluster from Streptomyces sclerotialus
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Location: 13,255 - 31,732 nt. (total: 18,478 nt).
This entry is originally from NCBI GenBank NZ_JOBC01000043.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001771
Short description scleric acid biosynthetic gene cluster from Streptomyces sclerotialus
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: NZ_JOBC01000043.1
Compounds
  • scleric acid
Species Streptomyces sclerotialus [taxonomy]
References
Chemical products information
scleric acid
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • IG96_RS0135470
  • WP_037773640.1
 13255 - 13881 (-) 4'-phosphopantetheinyl transferase superfamily protein
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  • IG96_RS0135475
  • WP_030624999.1
 13957 - 15117 (-) 2-oxo acid dehydrogenase subunit E2
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  • IG96_RS0135480
  • WP_030625001.1
 15114 - 16130 (-) alpha-ketoacid dehydrogenase subunit beta
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  • IG96_RS0135485
  • WP_078889003.1
 16127 - 17050 (-) thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha
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  • IG96_RS0135490
  • WP_030625009.1
 17047 - 17277 (-) acyl carrier protein
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  • IG96_RS0135495
  • WP_078889004.1
 17467 - 18099 (-) TetR/AcrR family transcriptional regulator
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  • IG96_RS37875
  • WP_196943382.1
 18415 - 19407 (+) gamma-butyrolactone biosynthesis protein
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  • IG96_RS0135505
  • WP_051872433.1
 19371 - 19691 (+) LysR family transcriptional regulator
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  • IG96_RS0135510
  • WP_030625021.1
 19745 - 20431 (+) HAD-IB family hydrolase
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  • IG96_RS0135515
  • WP_051872434.1
 20453 - 21043 (-) TetR/AcrR family transcriptional regulator
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  • IG96_RS0135520
  • WP_030625026.1
 21218 - 22354 (+) hypothetical protein
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  • IG96_RS37880
  • WP_051872436.1
 22635 - 25775 (+) non-ribosomal peptide synthetase
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  • IG96_RS0135530
  • WP_030625041.1
 25772 - 26503 (+) alpha/beta fold hydrolase
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  • IG96_RS0135535
  • WP_051872438.1
 26548 - 28518 (+) phenazine-specific anthranilate synthase
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  • IG96_RS0135540
  • WP_107054275.1
 28530 - 29732 (+) 3-deoxy-7-phosphoheptulonate synthase
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  • IG96_RS0135545
  • WP_030625033.1
 29754 - 30416 (+) isochorismatase family protein
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  • IG96_RS0135550
  • WP_030625035.1
 30413 - 31732 (+) peptide ligase PGM1-related protein
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
IG96_RS37880
Module ?
Specificity: proline
Evidence for specificity:
  • Structure-based inference
  • Mass spectrometry
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added NRP substrate specificities
Detailed domain annotation
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