BGC0001771 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001771 (Streptomyces sclerotialus)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS,butyrolactone	1	18,478	streptophenazine B / streptophenazine C / streptophenazine F / streptophenazine G / streptophenazine H	NRP + Polyketide	10%

BGC0001771 - Region 1 - NRPS,butyrolactone

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Location: 1 - 18,478 nt. (total: 18,478 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
butyrolactone: AfsA

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 18,479
Label		BGC0001771

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001771.1	1.35	NRP	scleric acid	Streptomyces sclerotialus
BGC0000849.1	0.70	Other, , (, B, u, t, y, r, o, l, a, c, t, o, n, e, )	SCB1, SCB2, SCB3	Streptomyces coelicolor A3(2)
BGC0000848.1	0.64	Other	A-factor	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000850.1	0.54	Other	γ-butyrolactone	Streptomyces acidiscabies
BGC0001480.1	0.37	Other	tundrenone	Methylobacter tundripaludum 21/22
BGC0001935.1	0.36	Other	3,7-dihydroxytropolone	Streptomyces cyaneofuscatus
BGC0001487.1	0.36	Other	3,7-dihydroxytropolone	Streptomyces cyaneofuscatus
BGC0001302.1	0.35	Other	lomofungin	Streptomyces lomondensis
BGC0001736.1	0.34	NRP	pepteridine A, pepteridine B	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001625.1	0.34	Polyketide	isofuranonaphthoquinone	Streptomyces sp. CB01883

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001771.1	1.00	NRP	scleric acid	Streptomyces sclerotialus
BGC0001935.1	0.69	Other	3,7-dihydroxytropolone	Streptomyces cyaneofuscatus
BGC0001487.1	0.69	Other	3,7-dihydroxytropolone	Streptomyces cyaneofuscatus
BGC0000849.1	0.68	Other, , (, B, u, t, y, r, o, l, a, c, t, o, n, e, )	SCB1, SCB2, SCB3	Streptomyces coelicolor A3(2)
BGC0000848.1	0.65	Other	A-factor	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000850.1	0.61	Other	γ-butyrolactone	Streptomyces acidiscabies
BGC0001251.1	0.60	NRP	epichloenin A	Epichloe festucae
BGC0001250.1	0.60	NRP	epichloenin A	Epichloe festucae
BGC0001633.1	0.59	Other	ketomemicin B3, ketomemicin B4	Streptomyces mobaraensis NBRC 13819 = DSM 40847
BGC0001480.1	0.59	Other	tundrenone	Methylobacter tundripaludum 21/22

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 18478:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pro)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

IG96_RS37880

Search NORINE for peptide: strict or relaxed

AMP-binding (463..859): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVQYcAmVVK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 80% (moderate)