BGC0001840: detoxin S1 biosynthetic gene cluster from Streptomyces sp. NRRL S-325
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 21,472 nt. (total: 21,472 nt).
This entry is originally from NCBI GenBank BK010707.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001840
Short description detoxin S1 biosynthetic gene cluster from Streptomyces sp. NRRL S-325
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
BK010707.1
via
Compounds
  • detoxin S1
Species Streptomyces sp. NRRL S-325 [taxonomy]
References
Chemical products information
detoxin S1 Evidence: MS/MS [1], [2]
Copy SMILES
C28H43N3O6
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ctg16_12
  • DAC80533.1
 1370 - 1780 (+) hypothetical protein
    copy AA seq
    copy Nt seq
    • ctg16_13
    • DAC80534.1
    		 1777 - 2157 (+) multi-component regulatory system-2 protein
      copy AA seq
      copy Nt seq
      • ctg16_14
      • DAC80535.1
      		 2132 - 2722 (+) putative ATP/GTP-binding protein
        copy AA seq
        copy Nt seq
        • ctg16_15
        • DAC80536.1
        		 2736 - 4109 (+) hypothetical protein
          copy AA seq
          copy Nt seq
          • ctg16_16
          • DAC80537.1
          		 4211 - 5464 (+) cytochrome P450
            copy AA seq
            copy Nt seq
            • ctg16_17
            • DAC80538.1
            		 5542 - 6306 (+) enoyl-CoA hydratase
              copy AA seq
              copy Nt seq
              • ctg16_18
              • DAC80539.1
              		 6474 - 7364 (-) TauD
                copy AA seq
                copy Nt seq
                • ctg16_19
                • DAC80540.1
                		 7432 - 16872 (-) nrps
                  copy AA seq
                  copy Nt seq
                  • ctg16_20
                  • DAC80541.1
                  		 16872 - 21011 (-) NRPS/PKS
                    copy AA seq
                    copy Nt seq
                    Biosynthesis information
                    Annotation changelog

                    Entry version: next

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2024-03-20
                    MIBiG v4 annotathon
                    • (ID: 3OFRGD3XQY2W5RRQYRWHG5KI)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 1

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2022-09-15
                    Submitted
                    • (ID: W7M5EW4IK7TDA54GG67QEM7H)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    2022-09-15
                    Added version to NCBI accession
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    2022-09-15
                    Fix DOI
                    • (ID: 3UOU7PODQJXIM6BEPUHHRRA5)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    Detailed domain annotation
                    Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                    A domain glossary is available here, and an explanation of the visualisation is available here.
                    Selected features only
                    Show module domains
                    Similar known gene clusters from MIBiG 4.0
                    Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                    Click on reference genes to show details of similarities to genes within the current region.
                    Click on an accession to open that entry in the MiBIG database.