BGC0001903 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001903 (Streptomyces sp. MA37)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	terpene	1	19,508	High	neocarazostatin A	other:other

BGC0001903 - Region 1 - terpene

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Location: 1 - 19,508 nt. (total: 19,508 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

Terpene

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 19,509
Label		BGC0001903

Tailoring functions

Oxidoreductases: oxidase

nzsG: pyruvate oxidase/decarboxylase

smcogs: SMCOG1055: pyruvate oxidase/decarboxylase

Transferases: aminotransferase

nzsC: aminotransferase

smcogs: SMCOG1019: aminotransferase

nzsJ: aminotransferase class V

smcogs: SMCOG1139: aminotransferase class V

Ligases: synthase

nzsE: 3-oxoacyl-(acyl carrier protein) synthase III

smcogs: SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III

nzsI: 3-oxoacyl-(acyl carrier protein) synthase III

smcogs: SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001903.3	1.00	other (other)	neocarazostatin A	Streptomyces sp. MA37
BGC0002554.2	0.83	other (other)	carquinostatin A, carquinostatin B	Streptomyces exfoliatus
BGC0001896.4	0.62	other (other)	carbazomycin B	Streptomyces luteoverticillatus
BGC0002711.2	0.48	PKS	nostovalerolactone, 9-dehydronostovalerolactone	Nostoc punctiforme PCC 73102
BGC0001206.5	0.46	other (other)	indolmycin	Streptomyces griseus subsp. griseus
BGC0000922.5	0.44	PKS	2-heptyl-3-hydroxy-4-quinolone, 2,4-Quinolinediol, 2-heptylquinolin-4(1H)-one	Pseudomonas aeruginosa PAO1
BGC0001361.3	0.43	terpene	sodorifen	Serratia plymuthica 4Rx13
BGC0002283.2	0.43	terpene	sodorifen	Serratia plymuthica
BGC0001651.3	0.40	other (other)	legionaminic acid	Tannerella forsythia 92A2
BGC0000925.5	0.39	other (other)	quinolobactin	Pseudomonas fluorescens

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001903.3	1.00	other (other)	neocarazostatin A	Streptomyces sp. MA37
BGC0002554.2	0.83	other (other)	carquinostatin A, carquinostatin B	Streptomyces exfoliatus
BGC0001896.4	0.62	other (other)	carbazomycin B	Streptomyces luteoverticillatus
BGC0002711.2	0.48	PKS	nostovalerolactone, 9-dehydronostovalerolactone	Nostoc punctiforme PCC 73102
BGC0001206.5	0.46	other (other)	indolmycin	Streptomyces griseus subsp. griseus
BGC0000922.5	0.44	PKS	2-heptyl-3-hydroxy-4-quinolone, 2,4-Quinolinediol, 2-heptylquinolin-4(1H)-one	Pseudomonas aeruginosa PAO1
BGC0001361.3	0.43	terpene	sodorifen	Serratia plymuthica 4Rx13
BGC0002283.2	0.43	terpene	sodorifen	Serratia plymuthica
BGC0001651.3	0.40	other (other)	legionaminic acid	Tannerella forsythia 92A2
BGC0000925.5	0.39	other (other)	quinolobactin	Pseudomonas fluorescens

Similar known clusters from MIBiG 4.0

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
triterpene	C30 carotenoid	diapophytoene	C30	acyclic	none
triterpene		squalene	C30	acyclic	none
triterpene		PSPP	C30	acyclic	PP
tetraterpene	C40 carotenoid	phytoene	C40	acyclic	none
triterpene		hydroxysqualene	C30	acyclic	OH

Genes with terpene domains:

nzsF: PT_phytoene_like

Domain 1 (53 - 360): Prenyltransferase; Phytoene synthase like

Subtype: unknown

Reactions:: FPP → diapophytoene; FPP → squalene; FPP → PSPP; GGPP → phytoene; PSPP → hydroxysqualene

Terpene

Glossary

Acronym	Full name
FPP	Farnesyl diphosphate
GGPP	Geranylgeranyl diphosphate
PP	Diphosphate
PSPP	Presqualene diphosphate