BGC0001913 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001913 (fungal sp. ATCC 74256)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	43,800	phomoidride	PKS	100%

BGC0001913 - Region 1 - T1PKS

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Location: 1 - 43,800 nt. (total: 43,800 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 43,801
Label		BGC0001913

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001913	1.00	Polyketide	phomoidride	fungal sp. ATCC 74256
BGC0002227	0.32	NRP	AKML B, AKML D, AKML A, AKML C	Aspergillus luchuensis IFO 4308
BGC0000046	0.32	Polyketide	depudecin	Alternaria brassicicola
BGC0001124	0.26	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0002228	0.26	NRP	CIML B, CIML A, CIML D, CIML C	Colletotrichum incanum
BGC0002180	0.25	Polyketide	(+)-asperlin, (2Z,4Z,6E)-octa-2,4,6-trienoic acid	Aspergillus nidulans FGSC A4
BGC0002266	0.24	Terpene, Polyketide	calidoustene A, calidoustene B, calidoustene C	Aspergillus calidoustus
BGC0002729	0.24	Polyketide	sordarial	Neurospora crassa OR74A
BGC0001749	0.23	Polyketide	epipyriculol	Pyricularia oryzae 70-15
BGC0002211	0.23	Polyketide	HEx-pks1 polyketide	Paraphaeosphaeria sporulosa

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001913	1.00	Polyketide	phomoidride	fungal sp. ATCC 74256
BGC0002227	0.66	NRP	AKML B, AKML D, AKML A, AKML C	Aspergillus luchuensis IFO 4308
BGC0000046	0.65	Polyketide	depudecin	Alternaria brassicicola
BGC0001124	0.60	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0002228	0.59	NRP	CIML B, CIML A, CIML D, CIML C	Colletotrichum incanum
BGC0002266	0.57	Terpene, Polyketide	calidoustene A, calidoustene B, calidoustene C	Aspergillus calidoustus
BGC0002729	0.57	Polyketide	sordarial	Neurospora crassa OR74A
BGC0001749	0.56	Polyketide	epipyriculol	Pyricularia oryzae 70-15
BGC0002211	0.56	Polyketide	HEx-pks1 polyketide	Paraphaeosphaeria sporulosa
BGC0002240	0.55	Polyketide	BAB, BAA	Metarhizium anisopliae

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 35751:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

phiA

PKS_AT (591..913): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 71.2
Methoxymalonyl-CoA: 66.8
Malonyl-CoA: 63.1
Isobutyryl-CoA: 49.3
Propionyl-CoA: 23.9
inactive: 15.3
Benzoyl-CoA: 13.5
CHC-CoA: 12.7
fatty_acid: 10.0
trans-1,2-CPDA: 8.2
2-Methylbutyryl-CoA: 5.8
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
Ethylmalonyl-CoA: -1.8