BGC0001941: Fulvuthiacene A biosynthetic gene cluster from Myxococcus fulvus
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 55,204 nt. (total: 55,204 nt).
This entry is originally from NCBI GenBank MH069655.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001941
Short description Fulvuthiacene A biosynthetic gene cluster from Myxococcus fulvus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Type I)
Loci
MH069655.1
via
Compounds
  • Fulvuthiacene A
  • Fulvuthiacene B
Species Myxococcus fulvus [taxonomy]
References
Chemical products information
Fulvuthiacene A Evidence: NMR [1]
Copy SMILES
C24H39N1O4S1
Chemical database entries
NPAtlas
Fulvuthiacene B Evidence: NMR [1]
Copy SMILES
C22H35N1O4S1
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AXM42940.1
  • orf1
 18 - 215 (+) lysine biosynthesis protein LysW
    copy AA seq
    copy Nt seq
    • AXM42941.1
    • orf2
    		 229 - 1092 (+) phage major capsid protein
      copy AA seq
      copy Nt seq
      • AXM42942.1
      • ftaN
      		 1115 - 2083 (-) methyl transferase type 11
        copy AA seq
        copy Nt seq
        • AXM42943.1
        • ftaM
        		 2216 - 4393 (-) FadJ-like protein
          copy AA seq
          copy Nt seq
          • AXM42944.1
          • ftaL
          		 4434 - 5645 (-) thioesterase
            copy AA seq
            copy Nt seq
            • AXM42945.1
            • ftaK
            		 5819 - 6352 (-) hypothetical protein
              copy AA seq
              copy Nt seq
              • AXM42946.1
              • ftaJ
              		 6496 - 7392 (-) bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5-10-methylene-tetrahydrofolate cyclohydrolase
                copy AA seq
                copy Nt seq
                • AXM42947.1
                • ftaI
                		 7488 - 8918 (-) S-adenosylhomocysteinase
                  copy AA seq
                  copy Nt seq
                  • AXM42948.1
                  • ftaA
                  		 9530 - 18913 (+) type 1 polyketide synthase
                    copy AA seq
                    copy Nt seq
                    • AXM42949.1
                    • ftaB
                    		 18910 - 28578 (+) hybrid type 1 PKS/NRPS
                      copy AA seq
                      copy Nt seq
                      • AXM42950.1
                      • ftaC
                      		 28619 - 34417 (+) polyketide synthase
                        copy AA seq
                        copy Nt seq
                        • AXM42951.1
                        • ftaD
                        		 34410 - 38480 (+) polyketide synthase
                          copy AA seq
                          copy Nt seq
                          • AXM42952.1
                          • ftaE
                          		 38477 - 43714 (+) non-ribosomal peptide synthetase
                            copy AA seq
                            copy Nt seq
                            • AXM42953.1
                            • ftaF
                            		 43730 - 44755 (+) alphahydroxyglycine hydrolase-like protein
                              copy AA seq
                              copy Nt seq
                              • AXM42954.1
                              • ftaG
                              		 44752 - 45660 (+) methyl transferase
                                copy AA seq
                                copy Nt seq
                                • AXM42955.1
                                • ftaH
                                		 45674 - 46726 (+) amide hydrolase
                                  copy AA seq
                                  copy Nt seq
                                  • AXM42956.1
                                  • orf3
                                  		 46749 - 48347 (-) lysyl endopeptidase
                                    copy AA seq
                                    copy Nt seq
                                    • AXM42957.1
                                    • orf4
                                    		 48673 - 48993 (+) hypothetical protein
                                      copy AA seq
                                      copy Nt seq
                                      • AXM42958.1
                                      • orf5
                                      		 49674 - 50147 (+) hypothetical protein
                                        copy AA seq
                                        copy Nt seq
                                        • AXM42959.1
                                        • orf6
                                        		 50179 - 52182 (+) thioredoxin
                                          copy AA seq
                                          copy Nt seq
                                          • AXM42960.1
                                          • orf7
                                          		 52206 - 52844 (+) hypothetical protein
                                            copy AA seq
                                            copy Nt seq
                                            • AXM42961.1
                                            • orf8
                                            		 53045 - 53734 (-) phage tail fiber protein
                                              copy AA seq
                                              copy Nt seq
                                              • AXM42962.1
                                              • orf9
                                              		 54084 - 54281 (-) hypothetical protein
                                                copy AA seq
                                                copy Nt seq
                                                • AXM42963.1
                                                • orf10
                                                		 54386 - 54952 (+) hypothetical protein
                                                  copy AA seq
                                                  copy Nt seq
                                                  Biosynthesis information
                                                  Annotation changelog

                                                  Entry version: next

                                                  Date
                                                  Changes
                                                  Submitters
                                                  Reviewers
                                                  2024-05-14
                                                  MIBiG v4 annotathon
                                                  • (ID: 2WNR2XEQAAZUROR7BJVHOLGH)
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                  Entry version: 2

                                                  Date
                                                  Changes
                                                  Submitters
                                                  Reviewers
                                                  2022-09-15
                                                  Added NRP substrate specificities
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                  Entry version: 1

                                                  Date
                                                  Changes
                                                  Submitters
                                                  Reviewers
                                                  2019-10-16
                                                  Submitted
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                  Detailed domain annotation
                                                  Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                                                  A domain glossary is available here, and an explanation of the visualisation is available here.
                                                  Selected features only
                                                  Show module domains
                                                  Similar known gene clusters from MIBiG 4.0
                                                  Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                                                  Click on reference genes to show details of similarities to genes within the current region.
                                                  Click on an accession to open that entry in the MiBIG database.