BGC0001975: atratumycin biosynthetic gene cluster from Streptomyces atratus
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Location: 1 - 69,292 nt. (total: 69,292 nt).
This entry is originally from NCBI GenBank MK370905.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001975
Short description atratumycin biosynthetic gene cluster from Streptomyces atratus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
MK370905.1
1 - 69292
via
Compounds
  • atratumycin
Species Streptomyces atratus [taxonomy]
References
Chemical products information
atratumycin Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QBG38760.1
1 - 1551 (+) histidine ammonia-lyase
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    • QBG38761.1
    1973 - 2377 (+) IS481 family transposase
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      • QBG38762.1
      4058 - 4972 (+) Atr1
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        • QBG38763.1
        4969 - 5946 (+) Atr2
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          • QBG38764.1
          6274 - 7164 (+) Atr3
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            • QBG38765.1
            7167 - 7934 (+) Atr4
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              • QBG38766.1
              8232 - 8486 (+) Atr5
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                • QBG38767.1
                8547 - 9809 (+) Atr6
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                  • QBG38768.1
                  9803 - 10948 (+) Atr7
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                    • QBG38769.1
                    10945 - 11898 (+) Atr8
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                      • QBG38770.1
                      11898 - 12749 (+) Atr9
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                        • QBG38771.1
                        12746 - 13717 (+) Atr10
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                          • QBG38772.1
                          13962 - 15062 (+) Atr11
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                            • QBG38773.1
                            15125 - 15364 (+) Atr12
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                              • QBG38774.1
                              15364 - 15822 (+) Atr13
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                                • QBG38775.1
                                15819 - 16298 (+) Atr14
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                                  • QBG38776.1
                                  16308 - 17054 (+) Atr15
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                                    • QBG38777.1
                                    17140 - 17760 (+) Atr16
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                                      • QBG38778.1
                                      17811 - 18023 (+) Atr17
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                                        • QBG38779.1
                                        18288 - 18776 (+) Atr18
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                                          • QBG38780.1
                                          19100 - 19663 (-) Atr19
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                                            • QBG38781.1
                                            19837 - 20028 (-) Atr20
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                                              • QBG38782.1
                                              20025 - 31823 (-) Atr21
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                                                • QBG38783.1
                                                31820 - 42898 (-) Atr22
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                                                  • QBG38784.1
                                                  42898 - 57465 (-) Atr23
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                                                    • QBG38785.1
                                                    57899 - 58138 (+) Atr24
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                                                      • QBG38786.1
                                                      58135 - 59106 (+) Atr25
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                                                        • QBG38787.1
                                                        59106 - 59432 (+) Atr26
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                                                          • QBG38788.1
                                                          59490 - 60761 (+) Atr27
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                                                            • QBG38789.1
                                                            60790 - 61254 (+) Atr28
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                                                              • QBG38790.1
                                                              61251 - 62207 (+) Atr29
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                                                                • QBG38791.1
                                                                62204 - 62992 (+) Atr30
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                                                                  • QBG38792.1
                                                                  63287 - 64312 (+) Atr31
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                                                                    • QBG38793.1
                                                                    64471 - 66474 (+) Atr32
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                                                                      • QBG38794.1
                                                                      66372 - 66755 (-) Atr32
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                                                                        • QBG38795.1
                                                                        66986 - 67273 (-) hypothetical protein
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                                                                          • QBG38796.1
                                                                          67427 - 67795 (+) hypothetical protein
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                                                                            • QBG38797.1
                                                                            68048 - 69292 (+) ErfK/YbiS/YcfS/YnhG family protein
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                                                                              Biosynthesis information

                                                                              Biosynthetic modules

                                                                              Name
                                                                              Unk01
                                                                              Type
                                                                              nrps-type1
                                                                              Genes
                                                                              QBG38782.1
                                                                              Substrates
                                                                              glycine (evidence: Structure-based inference [1])
                                                                              Integrated Monomers
                                                                              Domains
                                                                              adenylation
                                                                              Name
                                                                              Unk02
                                                                              Type
                                                                              nrps-type1
                                                                              Genes
                                                                              QBG38782.1
                                                                              Substrates
                                                                              leucine (evidence: Structure-based inference [1])
                                                                              Integrated Monomers
                                                                              Domains
                                                                              adenylation
                                                                              Name
                                                                              Unk03
                                                                              Type
                                                                              nrps-type1
                                                                              Genes
                                                                              QBG38782.1
                                                                              Substrates
                                                                              tyrosine (evidence: Structure-based inference [1])
                                                                              Integrated Monomers
                                                                              Domains
                                                                              adenylation
                                                                              Name
                                                                              Unk04
                                                                              Type
                                                                              nrps-type1
                                                                              Genes
                                                                              QBG38783.1
                                                                              Substrates
                                                                              phenylalanine (evidence: Structure-based inference [1])
                                                                              Integrated Monomers
                                                                              Domains
                                                                              adenylation
                                                                              Name
                                                                              Unk05
                                                                              Type
                                                                              nrps-type1
                                                                              Genes
                                                                              QBG38783.1
                                                                              Substrates
                                                                              proline (evidence: Structure-based inference [1])
                                                                              Integrated Monomers
                                                                              Domains
                                                                              adenylation
                                                                              Name
                                                                              Unk06
                                                                              Type
                                                                              nrps-type1
                                                                              Genes
                                                                              QBG38783.1
                                                                              Substrates
                                                                              valine (evidence: Structure-based inference [1])
                                                                              Integrated Monomers
                                                                              Domains
                                                                              adenylation
                                                                              Name
                                                                              Unk07
                                                                              Type
                                                                              nrps-type1
                                                                              Genes
                                                                              QBG38784.1
                                                                              Substrates
                                                                              threonine (evidence: Structure-based inference, Sequence-based prediction)
                                                                              Integrated Monomers
                                                                              Domains
                                                                              adenylation
                                                                              Name
                                                                              Unk08
                                                                              Type
                                                                              nrps-type1
                                                                              Genes
                                                                              QBG38784.1
                                                                              Substrates
                                                                              serine (evidence: Structure-based inference [1])
                                                                              Integrated Monomers
                                                                              Domains
                                                                              adenylation
                                                                              Name
                                                                              Unk09
                                                                              Type
                                                                              nrps-type1
                                                                              Genes
                                                                              QBG38784.1
                                                                              Substrates
                                                                              tryptophan (evidence: Structure-based inference [1])
                                                                              Integrated Monomers
                                                                              Domains
                                                                              adenylation
                                                                              Name
                                                                              Unk10
                                                                              Type
                                                                              nrps-type1
                                                                              Genes
                                                                              QBG38784.1
                                                                              Substrates
                                                                              asparagine (evidence: Structure-based inference [1])
                                                                              Integrated Monomers
                                                                              Domains
                                                                              adenylation
                                                                              Annotation changelog

                                                                              Entry version: 3

                                                                              Date
                                                                              Changes
                                                                              Submitters
                                                                              Reviewers
                                                                              Update chemical activity to schema version 2.11
                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                              Entry version: 2

                                                                              Date
                                                                              Changes
                                                                              Submitters
                                                                              Reviewers
                                                                              Updated bioactivity data
                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                              Added NRP substrate specificities
                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                              Entry version: 1

                                                                              Date
                                                                              Changes
                                                                              Submitters
                                                                              Reviewers
                                                                              Submitted
                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                              Detailed domain annotation
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