BGC0002012: julichrome Q3-3 biosynthetic gene cluster from Streptomyces afghaniensis 772
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 8,349 - 34,051 nt. (total: 25,703 nt).
This entry is originally from NCBI GenBank NZ_KE354310.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002012
Short description julichrome Q3-3 biosynthetic gene cluster from Streptomyces afghaniensis 772
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
NZ_KE354310.1
8349 - 34051
via
Compounds
  • julichrome Q3-3
  • julichrome Q3-5
Species Streptomyces afghaniensis 772 [taxonomy]
References
Chemical products information
julichrome Q3-3 Evidence:
(no structure information available)
julichrome Q3-5 Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • STAFG_RS30595
  • WP_037671479.1
 8349 - 8765 (-) Fur family transcriptional regulator
    copy AA seq
    copy Nt seq
    • STAFG_RS30600
    • WP_020275079.1
    		 8912 - 9304 (-) CBS domain-containing protein
      copy AA seq
      copy Nt seq
      • STAFG_RS30605
      • WP_020275080.1
      • hisN
      		 9482 - 10282 (-) histidinol-phosphatase
        copy AA seq
        copy Nt seq
        • STAFG_RS30610
        • WP_037671481.1
        		 10486 - 11094 (+) TetR/AcrR family transcriptional regulator
          copy AA seq
          copy Nt seq
          • STAFG_RS30615
          • WP_020275082.1
          		 11102 - 11425 (-) multidrug efflux SMR transporter
            copy AA seq
            copy Nt seq
            • STAFG_RS30620
            • WP_020275083.1
            • rsgA
            		 11573 - 12583 (-) ribosome small subunit-dependent GTPase A
              copy AA seq
              copy Nt seq
              • STAFG_RS30625
              • WP_020275084.1
              • aroA
              		 12601 - 13917 (-) 3-phosphoshikimate 1-carboxyvinyltransferase
                copy AA seq
                copy Nt seq
                • STAFG_RS30630
                • WP_020275085.1
                		 14015 - 14749 (-) M50 family metallopeptidase
                  copy AA seq
                  copy Nt seq
                  • STAFG_RS30635
                  • WP_020275086.1
                  		 14921 - 15775 (-) NAD(P)H-binding protein
                    copy AA seq
                    copy Nt seq
                    • STAFG_RS30640
                    • WP_020275087.1
                    		 15856 - 17316 (-) FAD-dependent oxidoreductase
                      copy AA seq
                      copy Nt seq
                      • STAFG_RS30645
                      • WP_020275088.1
                      		 17501 - 18709 (-) hypothetical protein
                        copy AA seq
                        copy Nt seq
                        • STAFG_RS30650
                        • WP_020275089.1
                        		 18706 - 19713 (-) LLM class F420-dependent oxidoreductase
                          copy AA seq
                          copy Nt seq
                          • STAFG_RS30655
                          • WP_020275090.1
                          		 19725 - 20951 (-) cytochrome P450
                            copy AA seq
                            copy Nt seq
                            • STAFG_RS30660
                            • WP_037671485.1
                            		 21126 - 21830 (-) TetR/AcrR family transcriptional regulator
                              copy AA seq
                              copy Nt seq
                              • STAFG_RS30665
                              • WP_020275092.1
                              		 22080 - 23543 (+) MFS transporter
                                copy AA seq
                                copy Nt seq
                                • STAFG_RS30670
                                • WP_082320004.1
                                		 23910 - 24716 (+) response regulator transcription factor
                                  copy AA seq
                                  copy Nt seq
                                  • STAFG_RS56080
                                  		 24974 - >25267 (+) TcmI family type II polyketide cyclase
                                    copy AA seq
                                    copy Nt seq
                                    • STAFG_RS56085
                                    • WP_037671497.1
                                    		 25322 - 25645 (+) TcmI family type II polyketide cyclase
                                      copy AA seq
                                      copy Nt seq
                                      • STAFG_RS30680
                                      • WP_020275095.1
                                      		 25642 - 26913 (+) beta-ketoacyl-[acyl-carrier-protein] synthase family protein
                                        copy AA seq
                                        copy Nt seq
                                        • STAFG_RS30685
                                        • WP_037671486.1
                                        		 26910 - 28103 (+) ketosynthase chain-length factor
                                          copy AA seq
                                          copy Nt seq
                                          • STAFG_RS30690
                                          • WP_020275097.1
                                          		 28184 - 28447 (+) acyl carrier protein
                                            copy AA seq
                                            copy Nt seq
                                            • STAFG_RS30695
                                            • WP_020275098.1
                                            		 28500 - 29285 (+) SDR family NAD(P)-dependent oxidoreductase
                                              copy AA seq
                                              copy Nt seq
                                              • STAFG_RS30700
                                              • WP_020275099.1
                                              		 29314 - 30264 (+) aromatase/cyclase
                                                copy AA seq
                                                copy Nt seq
                                                • STAFG_RS30705
                                                • WP_020275100.1
                                                		 30261 - 31169 (+) alpha/beta hydrolase
                                                  copy AA seq
                                                  copy Nt seq
                                                  • STAFG_RS30710
                                                  • WP_020275101.1
                                                  		 31166 - 31567 (+) lipocalin-like domain-containing protein
                                                    copy AA seq
                                                    copy Nt seq
                                                    • STAFG_RS54195
                                                    • WP_167338033.1
                                                    		 31564 - 31755 (+) hypothetical protein
                                                      copy AA seq
                                                      copy Nt seq
                                                      • STAFG_RS48165
                                                      • WP_020275103.1
                                                      		 31752 - 32486 (+) 4'-phosphopantetheinyl transferase superfamily protein
                                                        copy AA seq
                                                        copy Nt seq
                                                        • STAFG_RS30725
                                                        • WP_020275104.1
                                                        		 32578 - 33393 (+) SOS response-associated peptidase
                                                          copy AA seq
                                                          copy Nt seq
                                                          • STAFG_RS30730
                                                          • WP_020275105.1
                                                          		 33395 - 34051 (+) hypothetical protein
                                                            copy AA seq
                                                            copy Nt seq
                                                            Biosynthesis information
                                                            Annotation changelog

                                                            Entry version: 3

                                                            Date
                                                            Changes
                                                            Submitters
                                                            Reviewers
                                                            2022-10-07
                                                            Update chemical activity to schema version 2.11
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                            Entry version: 2

                                                            Date
                                                            Changes
                                                            Submitters
                                                            Reviewers
                                                            2022-09-15
                                                            Fixed DOIs
                                                            • (ID: CUSGWVK3I4TVHJH7NHPFAP2L)
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                            2022-09-15
                                                            Updated bioactivity data
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                            Entry version: 1

                                                            Date
                                                            Changes
                                                            Submitters
                                                            Reviewers
                                                            2019-10-16
                                                            Submitted
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                            Detailed domain annotation
                                                            Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                                                            A domain glossary is available here, and an explanation of the visualisation is available here.
                                                            Selected features only
                                                            Show module domains
                                                            Similar known gene clusters from MIBiG 4.0
                                                            Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                                                            Click on reference genes to show details of similarities to genes within the current region.
                                                            Click on an accession to open that entry in the MiBIG database.