BGC0002021: fogacin biosynthetic gene cluster from Actinoplanes missouriensis 431
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Location: 5,308,210 - 5,404,183 nt. (total: 95,974 nt).
This entry is originally from NCBI GenBank AP012319.1.

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General
Compounds
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Biosynthesis
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KnownClusterBlast
NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0002021
Short description fogacin biosynthetic gene cluster from Actinoplanes missouriensis 431
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
AP012319.1
5336641 - 5376856
via
Compounds
  • fogacin
  • fogacin B
  • fogacin C
Species Actinoplanes missouriensis 431 [taxonomy]
References
Chemical products information
fogacin Evidence:
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C16H18O6
Chemical database entries
PubCHEM
fogacin B Evidence:
(no structure information available)
fogacin C Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AMIS_50340
  • BAL90254.1
 5336644 - 5337045 (-) hypothetical protein
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    • AMIS_50350
    • BAL90255.1
    		 5337153 - 5338934 (-) putative beta-ketoacyl synthase
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      • AMIS_50360
      • BAL90256.1
      		 5338936 - 5339712 (-) putative enoyl-CoA hydratase/isomerase
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        • AMIS_50370
        • BAL90257.1
        		 5339709 - 5340449 (-) putative enoyl-CoA hydratase/isomerase
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          • AMIS_50380
          • BAL90258.1
          		 5340446 - 5341669 (-) putative 3-hydroxy-3-methylglutaryl-CoA synthase
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            • AMIS_50390
            • BAL90259.1
            		 5341666 - 5341911 (-) putative acyl carrier protein
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              • AMIS_50400
              • BAL90260.1
              		 5341908 - 5342855 (-) hypothetical protein
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                • AMIS_50410
                • BAL90261.1
                		 5342852 - 5343139 (-) putative acyl carrier protein
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                  • AMIS_50420
                  • BAL90262.1
                  		 5343210 - 5344421 (-) putative beta-ketoacyl synthase beta subunit
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                    • AMIS_50430
                    • BAL90263.1
                    		 5344418 - 5345686 (-) putative beta-ketoacyl synthase alpha subunit
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                      • AMIS_50440
                      • BAL90264.1
                      		 5345689 - 5345925 (-) putative acyl carrier protein
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                        • AMIS_50450
                        • BAL90265.1
                        		 5346040 - 5347164 (-) putative 3-oxoacyl-ACP synthase III
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                          • AMIS_50460
                          • BAL90266.1
                          		 5347386 - 5348126 (+) putative short-chain dehydrogenase
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                            • AMIS_50470
                            • BAL90267.1
                            		 5348219 - 5349265 (+) putative luciferase-like monooxygenase
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                              • AMIS_50480
                              • BAL90268.1
                              		 5349385 - 5349900 (+) hypothetical protein
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                                • AMIS_50490
                                • BAL90269.1
                                		 5349958 - 5351103 (-) putative oxidoreductase
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                                  • AMIS_50500
                                  • BAL90270.1
                                  		 5351656 - 5352507 (+) putative SARP-family transcriptional activator
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                                    • AMIS_50510
                                    • BAL90271.1
                                    		 5352546 - 5353469 (+) putative polyketide cyclase
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                                      • AMIS_50520
                                      • BAL90272.1
                                      		 5353535 - 5353984 (+) hypothetical protein
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                                        • AMIS_50530
                                        • BAL90273.1
                                        		 5354242 - 5355153 (+) hypothetical protein
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                                          • AMIS_50540
                                          • BAL90274.1
                                          		 5355362 - 5356570 (+) putative acyltransferase
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                                            • AMIS_50550
                                            • BAL90275.1
                                            		 5356567 - 5357766 (+) putative cytochrome P450
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                                              • AMIS_50560
                                              • BAL90276.1
                                              		 5357841 - 5359034 (-) hypothetical protein
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                                                • AMIS_50570
                                                • BAL90277.1
                                                		 5359062 - 5360222 (-) putative carboxylesterase
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                                                  • AMIS_50580
                                                  • BAL90278.1
                                                  		 5360457 - 5361815 (+) putative NDP-deoxyglucose-2,3-dehydratase
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                                                    • AMIS_50590
                                                    • BAL90279.1
                                                    		 5361812 - 5362936 (+) putative aminotransferase
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                                                      • AMIS_50600
                                                      • BAL90280.1
                                                      		 5362933 - 5363742 (+) putative methyltransferase
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                                                        • AMIS_50610
                                                        • BAL90281.1
                                                        		 5363739 - 5364332 (+) putative dTDP-4-dehydrorhamnose 3,5-epimerase
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                                                          • AMIS_50620
                                                          • BAL90282.1
                                                          		 5364329 - 5365327 (+) putative NAD-dependent epimerase/dehydratase
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                                                            • AMIS_50630
                                                            • BAL90283.1
                                                            		 5365412 - 5366545 (-) hypothetical protein
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                                                              • AMIS_50640
                                                              • BAL90284.1
                                                              		 5366722 - 5367987 (+) putative beta-ketoacyl synthase alpha subunit
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                                                                • AMIS_50650
                                                                • BAL90285.1
                                                                		 5367984 - 5369183 (+) putative beta-ketoacyl synthase beta subunit
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                                                                  • AMIS_50660
                                                                  • BAL90286.1
                                                                  		 5369180 - 5370154 (+) putative polyketide cyclase/dehydrase
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                                                                    • AMIS_50670
                                                                    • BAL90287.1
                                                                    		 5370151 - 5371341 (+) putative carboxylesterase
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                                                                      • AMIS_50680
                                                                      • BAL90288.1
                                                                      		 5371338 - 5372120 (+) putative short-chain dehydrogenase
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                                                                        • AMIS_50690
                                                                        • BAL90289.1
                                                                        		 5372287 - 5374017 (-) putative ABC transporter ATPase and permease protein
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                                                                          • AMIS_50700
                                                                          • BAL90290.1
                                                                          		 5374227 - 5375225 (+) putative dTDP-glucose-4,6-dehydratase
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                                                                            • AMIS_50710
                                                                            • BAL90291.1
                                                                            		 5375278 - 5376168 (+) putative glucose-1-phosphate thymidylyltransferase
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                                                                              • AMIS_50720
                                                                              • BAL90292.1
                                                                              		 5376266 - 5376853 (-) putative NADPH-dependent FMN reductase
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                                                                                Biosynthesis information

                                                                                No biosynthesis information available for this record.

                                                                                Annotation changelog

                                                                                Entry version: 2

                                                                                Date
                                                                                Changes
                                                                                Submitters
                                                                                Reviewers
                                                                                2022-09-15
                                                                                Rename fogacin A to fogacin to match publication
                                                                                • (ID: SJG3CBEHSM6A3I74YXLH6GLA)
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                Entry version: 1

                                                                                Date
                                                                                Changes
                                                                                Submitters
                                                                                Reviewers
                                                                                2019-10-16
                                                                                Submitted
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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