BGC0002039: coformycin biosynthetic gene cluster from Nocardia interforma ATCC 21072
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 30,309 nt. (total: 30,309 nt).
This entry is originally from NCBI GenBank KY682079.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002039
Short description coformycin biosynthetic gene cluster from Nocardia interforma ATCC 21072
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
Loci
KY682079.1
1 - 30309
via
Compounds
  • coformycin
  • formycin A
Species Nocardia interforma ATCC 21072 [taxonomy]
References
Chemical products information
coformycin Evidence:
Copy SMILES
Chemical database entries
NPAtlas
PubCHEM
formycin A Evidence:
Copy SMILES
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AVW82896.1
  • orf-1
 1 - 438 (-) hypothetical protein
    copy AA seq
    copy Nt seq
    • AVW82897.1
    • focS
    		 473 - 2059 (-) fumarate reductase/succinate dehydrogenase
      copy AA seq
      copy Nt seq
      • AVW82898.1
      • focE
      		 2574 - 3512 (+) putative monooxygenase
        copy AA seq
        copy Nt seq
        • AVW82899.1
        • focD
        		 3502 - 4836 (+) putative monooxygenase
          copy AA seq
          copy Nt seq
          • AVW82900.1
          • focG
          		 4913 - 5752 (+) transcriptional regulator
            copy AA seq
            copy Nt seq
            • AVW82901.1
            • focR
            		 5797 - 6852 (-) glycine/D-amino acid oxidase
              copy AA seq
              copy Nt seq
              • AVW82902.1
              • focM
              		 7018 - 8259 (+) phosphoribosylglycinamide synthetase
                copy AA seq
                copy Nt seq
                • AVW82903.1
                • focL
                		 8340 - 9521 (+) saccharopine dehydrogenase
                  copy AA seq
                  copy Nt seq
                  • AVW82904.1
                  • focK
                  		 9521 - 10831 (+) L-lysine N6-monooxygenase
                    copy AA seq
                    copy Nt seq
                    • AVW82905.1
                    • focJ
                    		 10857 - 12863 (+) methionine-tRNA ligase
                      copy AA seq
                      copy Nt seq
                      • AVW82906.1
                      • focI
                      		 12860 - 14161 (+) aminotransferase
                        copy AA seq
                        copy Nt seq
                        • AVW82907.1
                        • foc1
                        		 14192 - 14920 (+) SAICAR synthetase
                          copy AA seq
                          copy Nt seq
                          • AVW82908.1
                          • foc2
                          		 14910 - 15605 (+) short chain dehydrognase
                            copy AA seq
                            copy Nt seq
                            • AVW82909.1
                            • foc3
                            		 15605 - 16378 (+) hydrolase
                              copy AA seq
                              copy Nt seq
                              • AVW82910.1
                              • foc4
                              		 16380 - 17252 (+) ATP phosphoribosyltransferase
                                copy AA seq
                                copy Nt seq
                                • AVW82911.1
                                • focF
                                		 17282 - 18286 (-) phosphoglycerate dehydrogenase
                                  copy AA seq
                                  copy Nt seq
                                  • AVW82912.1
                                  • focU
                                  		 18424 - 19647 (+) phthalate 4,5-dioxygenase
                                    copy AA seq
                                    copy Nt seq
                                    • AVW82913.1
                                    • focA
                                    		 19679 - 20959 (+) adenylosuccinate synthetase
                                      copy AA seq
                                      copy Nt seq
                                      • AVW82914.1
                                      • focH
                                      		 20959 - 21522 (+) AICAR transformylase
                                        copy AA seq
                                        copy Nt seq
                                        • AVW82915.1
                                        • focQ
                                        		 21566 - 22729 (-) amidohydrolase
                                          copy AA seq
                                          copy Nt seq
                                          • AVW82916.1
                                          • focN
                                          		 22801 - 23502 (+) putative HAD superfamily hydrolase
                                            copy AA seq
                                            copy Nt seq
                                            • AVW82917.1
                                            • foc5
                                            		 23555 - 24739 (-) MFS transporter
                                              copy AA seq
                                              copy Nt seq
                                              • AVW82918.1
                                              • focB
                                              		 24768 - 26210 (-) adenylosuccinate lyase
                                                copy AA seq
                                                copy Nt seq
                                                • AVW82919.1
                                                • focT
                                                		 26207 - 27232 (-) Beta-ribofuranosylaminobenzene 5'-phosphate synthase
                                                  copy AA seq
                                                  copy Nt seq
                                                  • AVW82920.1
                                                  • focC
                                                  		 27246 - 28130 (-) SAICAR synthetase
                                                    copy AA seq
                                                    copy Nt seq
                                                    • AVW82921.1
                                                    • focX
                                                    		 28386 - 29252 (+) 6-phosphofructokinase
                                                      copy AA seq
                                                      copy Nt seq
                                                      • AVW82922.1
                                                      • focP
                                                      		 29216 - 29833 (+) NUDIX hydrolase
                                                        copy AA seq
                                                        copy Nt seq
                                                        • AVW82923.1
                                                        • Orf_1
                                                        		 29839 - 30309 (-) flavin reductase
                                                          copy AA seq
                                                          copy Nt seq
                                                          Biosynthesis information
                                                          Annotation changelog

                                                          Entry version: next

                                                          Date
                                                          Changes
                                                          Submitters
                                                          Reviewers
                                                          2024-08-10
                                                          MIBiG v4 annotathon
                                                          • (ID: 4CEPXXFDQQ46VQJXBT4B4AUO)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                          Entry version: 2

                                                          Date
                                                          Changes
                                                          Submitters
                                                          Reviewers
                                                          2022-10-07
                                                          Changed chemical structures for compounds: coformycin.
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          2022-10-07
                                                          Added NPAtlas links to compounds: coformycin.
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                          Entry version: 1

                                                          Date
                                                          Changes
                                                          Submitters
                                                          Reviewers
                                                          2022-09-15
                                                          Entry added
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                          Similar known gene clusters from MIBiG 4.0
                                                          Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                                                          Click on reference genes to show details of similarities to genes within the current region.
                                                          Click on an accession to open that entry in the MiBIG database.