BGC0002051: antipain biosynthetic gene cluster from Streptomyces sp.
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Location: 1 - 13,500 nt. (total: 13,500 nt).
This entry is originally from NCBI GenBank MT149901.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002051
Short description antipain biosynthetic gene cluster from Streptomyces sp.
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
MT149901.1
via
Compounds
  • antipain
Species Streptomyces sp. [taxonomy]
References
Chemical products information
antipain Evidence: Mass spectrometry
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Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • NAI38-460
  • QOE83921.1
  • efflux_transporter
 163 - 1470 (+) putative multidrug-efflux transporter
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    • NAI38-461
    • QOE83922.1
    • dhbF
    		 1588 - 2883 (+) dimodular nonribosomal peptide synthase
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      • NAI38-462
      • QOE83923.1
      • tycC
      		 3033 - 6227 (+) tyrocidine synthase 3
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        • NAI38-463
        • QOE83924.1
        • lgrD
        		 6224 - 8167 (+) linear gramicidin synthase subunit D
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          • NAI38-464
          • QOE83925.1
          • lgrB_1
          		 8169 - 10088 (+) linear gramicidin synthase subunit B
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            • NAI38-465
            • QOE83926.1
            • lgrB_2
            		 10078 - 12936 (+) linear gramicidin synthase subunit B
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              Biosynthesis information

              Biosynthetic modules

              Name
              Unk01
              Type
              nrps-type1
              Genes
              tycC
              Substrates
              arginine (evidence: Structure-based inference [2])
              Integrated Monomers
              Domains
              adenylation
              Name
              Unk02
              Type
              nrps-type1
              Genes
              lgrD
              Substrates
              phenylalanine (evidence: Structure-based inference [2])
              Integrated Monomers
              Domains
              adenylation
              Name
              Unk03
              Type
              nrps-type1
              Genes
              lgrB_1
              Substrates
              valine (evidence: Structure-based inference [2])
              Integrated Monomers
              Domains
              adenylation
              Annotation changelog

              Entry version: 1

              Date
              Changes
              Submitters
              Reviewers
              2022-09-15
              Submitted
              • (ID: LOOLDPJUN4VZBEJ3W5R2EHIG)
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
              2022-09-15
              Added version to NCBI accession
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
              2022-09-15
              Added NRP substrate specificities
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
              Detailed domain annotation
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