BGC0002078: omnipeptin biosynthetic gene cluster from uncultured bacterium
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 66,069 - 147,602 nt. (total: 81,534 nt).
This entry is originally from NCBI GenBank MN161665.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002078
Short description omnipeptin biosynthetic gene cluster from uncultured bacterium
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
MN161665.1
66069 - 147602
via Heterologous expression
Compounds
  • omnipeptin
Species uncultured bacterium [taxonomy]
References
Chemical products information
omnipeptin Evidence: NMR, Mass spectrometry
Copy SMILES
C64H82Cl1N13O22
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • QEO74976.1
 66069 - 66554 (-) omn1
    copy AA seq
    copy Nt seq
    • QEO74977.1
    		 66551 - 67843 (-) omn2
      copy AA seq
      copy Nt seq
      • QEO74978.1
      		 67850 - 69415 (-) omn3
        copy AA seq
        copy Nt seq
        • QEO74979.1
        		 69674 - 71332 (+) omn4
          copy AA seq
          copy Nt seq
          • QEO74980.1
          		 71329 - 71580 (+) omn5
            copy AA seq
            copy Nt seq
            • QEO74981.1
            		 71582 - 85063 (+) omn6
              copy AA seq
              copy Nt seq
              • QEO74982.1
              		 85060 - 104691 (+) omn7
                copy AA seq
                copy Nt seq
                • QEO74983.1
                		 104693 - 111586 (+) omn8
                  copy AA seq
                  copy Nt seq
                  • QEO74984.1
                  		 111604 - 111828 (+) omn9
                    copy AA seq
                    copy Nt seq
                    • QEO74985.1
                    		 111921 - 114254 (+) omn10
                      copy AA seq
                      copy Nt seq
                      • QEO74986.1
                      		 114258 - 115055 (+) omn11
                        copy AA seq
                        copy Nt seq
                        • QEO74987.1
                        		 115064 - 116236 (+) omn12
                          copy AA seq
                          copy Nt seq
                          • QEO74988.1
                          		 116233 - 117942 (+) omn13
                            copy AA seq
                            copy Nt seq
                            • QEO74989.1
                            		 117907 - 118683 (-) omn14
                              copy AA seq
                              copy Nt seq
                              • QEO74990.1
                              		 118683 - 119621 (-) omn15
                                copy AA seq
                                copy Nt seq
                                • QEO74991.1
                                		 119611 - 120834 (-) omn16
                                  copy AA seq
                                  copy Nt seq
                                  • QEO74992.1
                                  		 120831 - 121805 (-) omn17
                                    copy AA seq
                                    copy Nt seq
                                    • QEO74993.1
                                    		 121817 - 123025 (-) omn18
                                      copy AA seq
                                      copy Nt seq
                                      • QEO74994.1
                                      		 123022 - 123453 (-) omn19
                                        copy AA seq
                                        copy Nt seq
                                        • QEO74995.1
                                        		 123431 - 124318 (-) omn20
                                          copy AA seq
                                          copy Nt seq
                                          • QEO74996.1
                                          		 124480 - 127209 (-) omn21
                                            copy AA seq
                                            copy Nt seq
                                            • QEO74997.1
                                            		 127420 - 129849 (-) omn22
                                              copy AA seq
                                              copy Nt seq
                                              • QEO74998.1
                                              		 129843 - 130562 (-) omn23
                                                copy AA seq
                                                copy Nt seq
                                                • QEO74999.1
                                                		 130696 - 131892 (+) omn24
                                                  copy AA seq
                                                  copy Nt seq
                                                  • QEO75000.1
                                                  		 131865 - 132536 (+) omn25
                                                    copy AA seq
                                                    copy Nt seq
                                                    • QEO75001.1
                                                    		 132607 - 133794 (-) omn26
                                                      copy AA seq
                                                      copy Nt seq
                                                      • QEO75002.1
                                                      		 133950 - 134804 (+) omn27
                                                        copy AA seq
                                                        copy Nt seq
                                                        • QEO75003.1
                                                        		 134827 - 135624 (+) omn28
                                                          copy AA seq
                                                          copy Nt seq
                                                          • QEO75004.1
                                                          		 135621 - 136697 (+) omn29
                                                            copy AA seq
                                                            copy Nt seq
                                                            • QEO75005.1
                                                            		 136694 - 137845 (+) omn30
                                                              copy AA seq
                                                              copy Nt seq
                                                              • QEO75006.1
                                                              		 137839 - 138654 (+) omn31
                                                                copy AA seq
                                                                copy Nt seq
                                                                • QEO75007.1
                                                                		 138651 - 140099 (+) omn32
                                                                  copy AA seq
                                                                  copy Nt seq
                                                                  • QEO75008.1
                                                                  		 140096 - 140947 (+) omn33
                                                                    copy AA seq
                                                                    copy Nt seq
                                                                    • QEO75009.1
                                                                    		 140944 - 142005 (+) omn34
                                                                      copy AA seq
                                                                      copy Nt seq
                                                                      • QEO75010.1
                                                                      		 142002 - 143363 (+) omn35
                                                                        copy AA seq
                                                                        copy Nt seq
                                                                        • QEO75011.1
                                                                        		 143463 - 144257 (+) omn36
                                                                          copy AA seq
                                                                          copy Nt seq
                                                                          • QEO75012.1
                                                                          		 144261 - 144896 (+) omn37
                                                                            copy AA seq
                                                                            copy Nt seq
                                                                            • QEO75013.1
                                                                            		 144874 - 145485 (-) omn38
                                                                              copy AA seq
                                                                              copy Nt seq
                                                                              • QEO75014.1
                                                                              		 145632 - 146594 (+) omn39
                                                                                copy AA seq
                                                                                copy Nt seq
                                                                                • QEO75015.1
                                                                                		 146658 - 147602 (+) omn40
                                                                                  copy AA seq
                                                                                  copy Nt seq
                                                                                  Biosynthesis information

                                                                                  Biosynthetic modules

                                                                                  Name
                                                                                  1
                                                                                  Type
                                                                                  nrps-type1
                                                                                  Genes
                                                                                  QEO74981.1
                                                                                  Substrates
                                                                                  aspartic acid branched (evidence: Structure-based inference, Heterologous expression)
                                                                                  Integrated Monomers
                                                                                  Domains
                                                                                  adenylation
                                                                                  Name
                                                                                  2
                                                                                  Type
                                                                                  nrps-type1
                                                                                  Genes
                                                                                  QEO74981.1
                                                                                  Substrates
                                                                                  beta-hydroxytyrosine (evidence: Structure-based inference, Heterologous expression)
                                                                                  Integrated Monomers
                                                                                  Domains
                                                                                  adenylation
                                                                                  Name
                                                                                  3
                                                                                  Type
                                                                                  nrps-type1
                                                                                  Genes
                                                                                  QEO74981.1
                                                                                  Substrates
                                                                                  serine (evidence: Structure-based inference, Heterologous expression)
                                                                                  Integrated Monomers
                                                                                  Domains
                                                                                  adenylation
                                                                                  Name
                                                                                  4
                                                                                  Type
                                                                                  nrps-type1
                                                                                  Genes
                                                                                  QEO74981.1
                                                                                  Substrates
                                                                                  glutamic acid (evidence: Structure-based inference, Heterologous expression)
                                                                                  Integrated Monomers
                                                                                  Domains
                                                                                  adenylation
                                                                                  Name
                                                                                  5
                                                                                  Type
                                                                                  nrps-type1
                                                                                  Genes
                                                                                  QEO74982.1
                                                                                  Substrates
                                                                                  threonine (evidence: Structure-based inference, Heterologous expression)
                                                                                  Integrated Monomers
                                                                                  Domains
                                                                                  adenylation
                                                                                  Name
                                                                                  6
                                                                                  Type
                                                                                  nrps-type1
                                                                                  Genes
                                                                                  QEO74982.1
                                                                                  Substrates
                                                                                  serine (evidence: Structure-based inference, Heterologous expression)
                                                                                  Integrated Monomers
                                                                                  Domains
                                                                                  adenylation
                                                                                  Name
                                                                                  7
                                                                                  Type
                                                                                  nrps-type1
                                                                                  Genes
                                                                                  QEO74982.1
                                                                                  Substrates
                                                                                  Integrated Monomers
                                                                                  Domains
                                                                                  adenylation
                                                                                  Name
                                                                                  8
                                                                                  Type
                                                                                  nrps-type1
                                                                                  Genes
                                                                                  QEO74982.1
                                                                                  Substrates
                                                                                  3-methylasparagine (evidence: Structure-based inference, Heterologous expression)
                                                                                  Integrated Monomers
                                                                                  Domains
                                                                                  adenylation
                                                                                  Name
                                                                                  9
                                                                                  Type
                                                                                  nrps-type1
                                                                                  Genes
                                                                                  QEO74982.1
                                                                                  Substrates
                                                                                  6-chlorotryptophan (evidence: Structure-based inference, Heterologous expression)
                                                                                  Integrated Monomers
                                                                                  Domains
                                                                                  adenylation
                                                                                  Name
                                                                                  10
                                                                                  Type
                                                                                  nrps-type1
                                                                                  Genes
                                                                                  QEO74982.1
                                                                                  Substrates
                                                                                  valine (evidence: Structure-based inference, Heterologous expression)
                                                                                  Integrated Monomers
                                                                                  Domains
                                                                                  adenylation
                                                                                  Name
                                                                                  11
                                                                                  Type
                                                                                  nrps-type1
                                                                                  Genes
                                                                                  QEO74983.1
                                                                                  Substrates
                                                                                  phenylalanine (evidence: Structure-based inference, Heterologous expression)
                                                                                  Integrated Monomers
                                                                                  Domains
                                                                                  adenylation
                                                                                  Name
                                                                                  12
                                                                                  Type
                                                                                  nrps-type1
                                                                                  Genes
                                                                                  QEO74983.1
                                                                                  Substrates
                                                                                  3-hydroxy-4-methylproline (evidence: Structure-based inference, Heterologous expression)
                                                                                  Integrated Monomers
                                                                                  Domains
                                                                                  adenylation
                                                                                  Annotation changelog

                                                                                  Entry version: 1

                                                                                  Date
                                                                                  Changes
                                                                                  Submitters
                                                                                  Reviewers
                                                                                  2022-09-15
                                                                                  Submitted
                                                                                  • (ID: KZLBDERD7NZFELVOLOQJLADT)
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                  2022-09-15
                                                                                  Added version to NCBI accession
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                  2022-09-15
                                                                                  Added NRP substrate specificities
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                  Detailed domain annotation
                                                                                  Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                                                                                  A domain glossary is available here, and an explanation of the visualisation is available here.
                                                                                  Selected features only
                                                                                  Show module domains
                                                                                  Similar known gene clusters from MIBiG 4.0
                                                                                  Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                                                                                  Click on reference genes to show details of similarities to genes within the current region.
                                                                                  Click on an accession to open that entry in the MiBIG database.