BGC0002086: rosamicin biosynthetic gene cluster from Micromonospora carbonacea
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Location: 1,361,829 - 1,422,030 nt. (total: 60,202 nt).
This entry is originally from NCBI GenBank CP058322.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0002086
Short description rosamicin biosynthetic gene cluster from Micromonospora carbonacea
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
CP058322.1
1361829 - 1422030
via
Compounds
  • rosamicin
Species Micromonospora carbonacea [taxonomy]
References
Chemical products information
rosamicin Evidence: NMR
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Chemical database entries
PubCHEM
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • HXZ27_06100
  • QLD23832.2
  • rosA
 1361829 - 1363511 (+) ABC-F type ribosomal protection protein
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    • HXZ27_06105
    • QLD28379.2
    • rosB
    		 1363556 - 1364350 (-) thioesterase
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      • HXZ27_06110
      • QLD23833.1
      • rosC
      		 1364457 - 1365689 (-) cytochrome P450
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        • HXZ27_06115
        • QLD23834.1
        • rosD
        		 1366193 - 1367401 (+) cytochrome P450
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          • HXZ27_06120
          • QLD23835.2
          • rosE
          		 1367530 - 1380945 (+) SDR family NAD(P)-dependent oxidoreductase
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            • HXZ27_06125
            • QLD23836.1
            • rosF
            		 1380972 - 1386749 (+) SDR family NAD(P)-dependent oxidoreductase
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              • HXZ27_06130
              • QLD28380.2
              • rosG
              		 1386821 - 1398064 (+) SDR family NAD(P)-dependent oxidoreductase
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                • HXZ27_06135
                • QLD23837.1
                • rosH
                		 1398126 - 1402850 (+) SDR family NAD(P)-dependent oxidoreductase
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                  • HXZ27_06140
                  • QLD23838.1
                  • rosI
                  		 1402883 - 1408237 (+) SDR family NAD(P)-dependent oxidoreductase
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                    • HXZ27_06145
                    • QLD23839.2
                    • rosJ
                    		 1408234 - 1409628 (+) P450-derived glycosyltransferase activator
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                      • HXZ27_06150
                      • QLD23840.2
                      • rosK
                      		 1409628 - 1410917 (+) activator-dependent family glycosyltransferase
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                        • HXZ27_06155
                        • QLD23841.2
                        • rosL
                        		 1410926 - 1411648 (+) class I SAM-dependent methyltransferase
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                          • HXZ27_06160
                          • QLD28381.2
                          • rosM
                          		 1411702 - 1413060 (+) crotonyl-CoA carboxylase/reductase
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                            • HXZ27_06165
                            • QLD23842.1
                            • rosN
                            		 1413247 - 1415250 (+) helix-turn-helix domain-containing protein
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                              • HXZ27_06170
                              • QLD23843.1
                              • rosO
                              		 1415192 - 1416403 (-) transposase
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                                • HXZ27_06175
                                • QLD23844.1
                                • rosP
                                		 1416731 - 1418176 (+) GTPase HflX
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                                  • HXZ27_06180
                                  • QLD23845.1
                                  • rosQ
                                  		 1418242 - 1419468 (+) dTDP-4-dehydro-6-deoxyglucose aminotransferase
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                                    • HXZ27_06185
                                    • QLD23846.2
                                    • rosR
                                    		 1419491 - 1420957 (+) dTDP-4-amino-4,6-dideoxy-D-glucose ammonia-lyase
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                                      • HXZ27_06190
                                      • QLD23847.1
                                      • rosS
                                      		 1421197 - 1422030 (+) 23S ribosomal RNA methyltransferase Erm
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                                        Biosynthesis information
                                        Annotation changelog

                                        Entry version: 2

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        2022-10-07
                                        Update chemical activity to schema version 2.11
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                        Entry version: 1

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        2022-09-15
                                        Submitted
                                        • (ID: VXQQS2VBYGA6KXCJ4IF2SC56)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        2022-09-15
                                        Added version to NCBI accession
                                        • (ID: AYT6WP6PINVPWSBOCVXGSMXM)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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