BGC0002139 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002139 (Aspergillus burnettii)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	22,912	burnettiene A/preburnettiene B/preburnettiene A	PKS:Iterative type I	100%

BGC0002139 - Region 1 - T1PKS

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Location: 1 - 22,912 nt. (total: 22,912 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 22,913
Label		BGC0002139

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002139	1.00	Polyketide	burnettiene A, preburnettiene B, preburnettiene A	Aspergillus burnettii FRR 5400
BGC0001254	0.35	Polyketide	ACT-Toxin II	Alternaria alternata
BGC0002745	0.35	Polyketide	verrucosidin	Penicillium polonicum
BGC0002258	0.34	Polyketide	shimalactone A, shimalactone B	Aspergillus stellatus
BGC0002192	0.33	Polyketide	FR901512	fungal sp. No.14919
BGC0002321	0.32	Other	pulcherriminic acid, pulcherrimin, cyclodileucine, compound 3	Metschnikowia aff. pulcherrima
BGC0001998	0.31	Polyketide	aspernidgulene A1, aspernidgulene A2, aspernidgulene B1	Aspergillus nidulans FGSC A4
BGC0001400	0.31	Polyketide	citreoviridin	Aspergillus terreus NIH2624
BGC0001907	0.26	Polyketide	chromane	Daldinia eschscholzii IFB-TL01
BGC0001268	0.24	NRP, Polyketide	fusarin C	Fusarium fujikuroi

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002139	1.00	Polyketide	burnettiene A, preburnettiene B, preburnettiene A	Aspergillus burnettii FRR 5400
BGC0001254	0.68	Polyketide	ACT-Toxin II	Alternaria alternata
BGC0002745	0.68	Polyketide	verrucosidin	Penicillium polonicum
BGC0002258	0.67	Polyketide	shimalactone A, shimalactone B	Aspergillus stellatus
BGC0002192	0.66	Polyketide	FR901512	fungal sp. No.14919
BGC0002321	0.65	Other	pulcherriminic acid, pulcherrimin, cyclodileucine, compound 3	Metschnikowia aff. pulcherrima
BGC0001998	0.65	Polyketide	aspernidgulene A1, aspernidgulene A2, aspernidgulene B1	Aspergillus nidulans FGSC A4
BGC0001400	0.64	Polyketide	citreoviridin	Aspergillus terreus NIH2624
BGC0001907	0.59	Polyketide	chromane	Daldinia eschscholzii IFB-TL01
BGC0001268	0.57	NRP, Polyketide	fusarin C	Fusarium fujikuroi

Similar known gene clusters from MIBiG 4.0

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 22912:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Me-pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ETB97_004590

PKS_AT (552..869): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 62.5%; Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 84.9
Methoxymalonyl-CoA: 72.1
Ethylmalonyl-CoA: 58.9
Malonyl-CoA: 40.0
Benzoyl-CoA: 34.5
Isobutyryl-CoA: 32.8
trans-1,2-CPDA: 31.2
Propionyl-CoA: 30.7
fatty_acid: 26.5
3-Methylbutyryl-CoA: 19.6
2-Methylbutyryl-CoA: 17.8
CHC-CoA: 15.8
Acetyl-CoA: 12.9
inactive: 0.0