BGC0002180 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002180 (Aspergillus nidulans FGSC A4)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	25,173	(+)-asperlin/(2Z,4Z,6E)-octa-2,4,6-trienoic acid	PKS	100%

BGC0002180 - Region 1 - T1PKS

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Location: 1 - 25,173 nt. (total: 25,173 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 25,174
Label		BGC0002180

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002180	1.00	Polyketide	(+)-asperlin, (2Z,4Z,6E)-octa-2,4,6-trienoic acid	Aspergillus nidulans FGSC A4
BGC0002391	0.32	Terpene	zealexin B2, zealexin C2	Zea mays
BGC0002610	0.32	Terpene	stellatic acid	Aspergillus stellatus
BGC0001124	0.27	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0002228	0.26	NRP	CIML B, CIML A, CIML D, CIML C	Colletotrichum incanum
BGC0002227	0.25	NRP	AKML B, AKML D, AKML A, AKML C	Aspergillus luchuensis IFO 4308
BGC0001264	0.23	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0002643	0.23	Alkaloid	aetokthonotoxin	Aetokthonos hydrillicola Thurmond2011
BGC0002207	0.22	Other	psilocybin	Psilocybe cyanescens
BGC0002211	0.21	Polyketide	HEx-pks1 polyketide	Paraphaeosphaeria sporulosa

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002180	1.00	Polyketide	(+)-asperlin, (2Z,4Z,6E)-octa-2,4,6-trienoic acid	Aspergillus nidulans FGSC A4
BGC0002391	0.65	Terpene	zealexin B2, zealexin C2	Zea mays
BGC0002610	0.65	Terpene	stellatic acid	Aspergillus stellatus
BGC0001124	0.60	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0002228	0.59	NRP	CIML B, CIML A, CIML D, CIML C	Colletotrichum incanum
BGC0002227	0.59	NRP	AKML B, AKML D, AKML A, AKML C	Aspergillus luchuensis IFO 4308
BGC0001264	0.57	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0002643	0.56	Alkaloid	aetokthonotoxin	Aetokthonos hydrillicola Thurmond2011
BGC0002207	0.55	Other	psilocybin	Psilocybe cyanescens
BGC0002211	0.54	Polyketide	HEx-pks1 polyketide	Paraphaeosphaeria sporulosa

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 25173:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ANIA_11191

PKS_AT (608..931): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; Methylmalonyl-CoA: 62.5%; Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 85.9
Methoxymalonyl-CoA: 85.0
Malonyl-CoA: 58.7
Isobutyryl-CoA: 56.7
Propionyl-CoA: 46.2
Ethylmalonyl-CoA: 42.4
inactive: 33.7
2-Methylbutyryl-CoA: 27.5
trans-1,2-CPDA: 27.2
3-Methylbutyryl-CoA: 21.7
CHC-CoA: 21.1
Acetyl-CoA: 17.4
fatty_acid: 16.5
Benzoyl-CoA: 15.2