BGC0002199 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002199 (Aspergillus nanangensis)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS,indole	1	17,425	nanangelenin A	other:other	100%

BGC0002199 - Region 1 - NRPS,indole

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Location: 1 - 17,425 nt. (total: 17,425 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
indole: (indsynth or dmat or indole_PTase)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 17,426
Label		BGC0002199

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002199	2.00	Alkaloid	nanangelenin A	Aspergillus nanangensis
BGC0000900	0.66	Other	ferrichrome	Aspergillus oryzae
BGC0001249	0.63	NRP	dimethylcoprogen	Alternaria alternata
BGC0002157	0.59	NRP, Alkaloid	(-)-ditryptophenaline	Aspergillus flavus
BGC0000293	0.57	NRP	acetylaszonalenin	Aspergillus fischeri NRRL 181
BGC0001261	0.57	NRP	AM-toxin	Alternaria alternata
BGC0000901	0.52	Other	ferrichrome	Aspergillus niger
BGC0001132	0.51	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0000313	0.51	NRP	beauvericin	Beauveria bassiana
BGC0000342	0.50	NRP	enniatin	Fusarium equiseti

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002199	1.00	Alkaloid	nanangelenin A	Aspergillus nanangensis
BGC0000900	0.66	Other	ferrichrome	Aspergillus oryzae
BGC0001249	0.65	NRP	dimethylcoprogen	Alternaria alternata
BGC0002157	0.63	NRP, Alkaloid	(-)-ditryptophenaline	Aspergillus flavus
BGC0000293	0.62	NRP	acetylaszonalenin	Aspergillus fischeri NRRL 181
BGC0001261	0.62	NRP	AM-toxin	Alternaria alternata
BGC0000901	0.60	Other	ferrichrome	Aspergillus niger
BGC0001132	0.59	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0000313	0.59	NRP	beauvericin	Beauveria bassiana
BGC0000342	0.58	NRP	enniatin	Fusarium equiseti

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 17425:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - Tyr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

FE257_001452

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AMP-binding (231..637): X

nrpys: Ant

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: GIILFGVGVK
Nearest Stachelhaus code(s):: Ant GIILFGVGVK (91% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1338..1735): Tyr

nrpys: Tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: tyr (Tyr)

Stachelhaus prediction details:

Stachelhaus sequence:: DAGMTMGVAK
Nearest Stachelhaus code(s):: Kyn DAAMIMGIAK (76% 8Å match)
Stachelhaus code match:: 70% (weak)