BGC0002225 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002225 (Aspergillus aculeatus ATCC 16872)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	18,926	aculene A/aculene B/aculene C/asperaculane A/asperaculane B/aculene D	terpene	100%

BGC0002225 - Region 1 - NRPS

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Location: 1 - 18,926 nt. (total: 18,926 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

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transport-related genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 18,927
Label		BGC0002225

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002225	1.00	Terpene	aculene A, aculene B, aculene C, asperaculane A, asperaculane B, aculene D	Aspergillus aculeatus ATCC 16872
BGC0000677	0.33	Terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0000900	0.33	Other	ferrichrome	Aspergillus oryzae
BGC0002245	0.33	Terpene	terpestacin, preterpestacin 3, preterpestacin 2, preterpestacin 1	Bipolaris maydis C5
BGC0001893	0.33	Other	abscisic acid	Botrytis cinerea B05.10
BGC0001249	0.32	NRP	dimethylcoprogen	Alternaria alternata
BGC0002219	0.32	Terpene	(-)-(R)-nephthenol	Stereum hirsutum FP-91666 SS1
BGC0002610	0.32	Terpene	stellatic acid	Aspergillus stellatus
BGC0002391	0.31	Terpene	zealexin B2, zealexin C2	Zea mays
BGC0002181	0.31	Terpene	pleuromutilin	Rhodocybe pseudopiperita

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002225	1.00	Terpene	aculene A, aculene B, aculene C, asperaculane A, asperaculane B, aculene D	Aspergillus aculeatus ATCC 16872
BGC0000677	0.66	Terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0000900	0.66	Other	ferrichrome	Aspergillus oryzae
BGC0002245	0.66	Terpene	terpestacin, preterpestacin 3, preterpestacin 2, preterpestacin 1	Bipolaris maydis C5
BGC0001893	0.66	Other	abscisic acid	Botrytis cinerea B05.10
BGC0001249	0.66	NRP	dimethylcoprogen	Alternaria alternata
BGC0002219	0.65	Terpene	(-)-(R)-nephthenol	Stereum hirsutum FP-91666 SS1
BGC0002610	0.65	Terpene	stellatic acid	Aspergillus stellatus
BGC0002391	0.65	Terpene	zealexin B2, zealexin C2	Zea mays
BGC0002181	0.64	Terpene	pleuromutilin	Rhodocybe pseudopiperita

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 18926:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Val)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ASPACDRAFT_29371

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AMP-binding (19..418): Val

nrpys: Val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DILFVGLVGK
Nearest Stachelhaus code(s):: Val DALFVGLVAK (53% 8Å match); mePip DMLFVGLGGK (47% 8Å match)
Stachelhaus code match:: 80% (moderate)