BGC0002278 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002278 (Penicillium brasilianum)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS-like	1	28,520	brasiliamide I/brasiliamide A/brasiliamide B/2,2-dibenzylpiperazine/brasiliamide D	other:other+NRPS:Type I	100%

BGC0002278 - Region 1 - NRPS-like

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Location: 1 - 28,520 nt. (total: 28,520 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 28,521
Label		BGC0002278

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002278	1.00	Alkaloid, NRP	brasiliamide I, brasiliamide A, brasiliamide B, 2,2-dibenzylpiperazine, brasiliamide D	Penicillium brasilianum
BGC0001168	0.32	NRP	livipeptin	Streptomyces lividans 1326
BGC0002610	0.32	Terpene	stellatic acid	Aspergillus stellatus
BGC0002602	0.30	Alkaloid	aspergillic acid	Aspergillus flavus
BGC0001516	0.30	NRP	aspergillic acid	Aspergillus flavus NRRL3357
BGC0002582	0.29	NRP	guanipiperazine A, guanipiperazine B	Streptomyces chrestomyceticus
BGC0001599	0.27	NRP	fragin	Burkholderia cenocepacia H111
BGC0001528	0.26	Terpene	betaestacin	Phoma betae
BGC0002348	0.24	NRP	aspulvinone E	Aspergillus terreus NIH2624
BGC0000894	0.23	Other	citrinin	Monascus aurantiacus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002278	1.00	Alkaloid, NRP	brasiliamide I, brasiliamide A, brasiliamide B, 2,2-dibenzylpiperazine, brasiliamide D	Penicillium brasilianum
BGC0001168	0.65	NRP	livipeptin	Streptomyces lividans 1326
BGC0002610	0.65	Terpene	stellatic acid	Aspergillus stellatus
BGC0002602	0.64	Alkaloid	aspergillic acid	Aspergillus flavus
BGC0001516	0.64	NRP	aspergillic acid	Aspergillus flavus NRRL3357
BGC0002582	0.62	NRP	guanipiperazine A, guanipiperazine B	Streptomyces chrestomyceticus
BGC0001599	0.61	NRP	fragin	Burkholderia cenocepacia H111
BGC0001528	0.59	Terpene	betaestacin	Phoma betae
BGC0002348	0.57	NRP	aspulvinone E	Aspergillus terreus NIH2624
BGC0000894	0.56	Other	citrinin	Monascus aurantiacus

Similar known gene clusters from MIBiG 4.0

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 28520:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Phe)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

PMG11_03954

Search NORINE for peptide: strict or relaxed

AMP-binding (26..430): Phe

nrpys: Phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: ala (Ala)

Stachelhaus prediction details:

Stachelhaus sequence:: DVFALGAVYK
Nearest Stachelhaus code(s):: Phe DVFALGAVYK (100% 8Å match)
Stachelhaus code match:: 100% (strong)